Evidence map›Paper›PMID 40627442›Full record

ArticleThe Journal of clinical investigation2025

Type 1 classical dendritic cells govern long-term cardiac allograft acceptance.

Macee C Owen, Vinay R Penna, Hao Dun, Wenjun Li, Benjamin J Kopecky, Kenneth M Murphy, Daniel Kreisel, Kory J Lavine

Abstract read
In one paragraph

Article in The Journal of clinical investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The DC1 conundrum: Do type I dendritic cells make or break allograft tolerance?American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Macee C OwenDepartment of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
Vinay R PennaDepartment of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.
Hao DunDepartment of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Wenjun LiDepartment of Surgery.
Benjamin J KopeckyDepartment of Surgery.
Kenneth M MurphyDepartment of Pathology & Immunology, and.
Daniel KreiselDepartment of Surgery.
Kory J LavineDepartment of Medicine, Washington University School of Medicine, St. Louis, Missouri, USA.

Funding

Specification and Function of Tissue Resident and Recruited Macrophages in Cardiac Remodeling and Heart FailureR35HL161185 · NHLBI · WASHINGTON UNIVERSITY · PI Kory J. Lavine · 2022 to 2026
$4.3M
Classical dendritic cells (cDC1) govern cardiac allograft toleranceF31AI194609 · NIAID · WASHINGTON UNIVERSITY · PI Macee Owen · 2025 to 2026
$77k
NHLBI NIH HHS R35 HL161185NIAID NIH HHS F31 AI194609
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CardiologyInflammationOrgan transplantation

Identifiers

PMID40627442
PMCPMC12435831

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.