ArticleHormones (Athens, Greece)2025
Utility of pan-immune-inflammation index in the diagnosis of masked hypertension in patients with type 2 diabetes mellitus.
Article in Hormones (Athens, Greece), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Article
- The Clinical Significance and Prognostic Value of Inflammatory Hematological Indices in Young Patients with Coronary Artery Disease.Journal of inflammation research · 2026Article
- Parathyroid disease, gut microbiome, biologic age, and more.Hormones (Athens, Greece) · 2025Article
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4 authors.
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Abstract
BACKGROUND AND
objectiveMasked hypertension (MHT) is a specific pattern of hypertension (HT) wherein office BP is normal despite elevated BP measured using ambulatory blood pressure monitoring (ABPM). Pan-immune-inflammation value (PIV) is a novel inflammatory parameter with diagnostic and prognostic significance in a number of disease conditions. In this study, we aimed to investigate the diagnostic utility of PIV in MHT in outpatient clinic settings in seemingly normotensive patients with type 2 diabetes mellitus (T2DM).
methodsWe retrospectively included 78 MTH, 120 sustained hypertensive (SHT), and 176 normotensive patients with T2DM. 24 h-ABPM was used to detect MHT. PIV was calculated as neutrophil/lymphocyte x platelet x monocyte and compared between the groups.
resultsPIV was greater in MHT and SHT groups compared with the controls [310 (267–355), 353 (222.1-455.2) and 247.2 (195.3–340), respectively, p < 0.001). hs-CRP was found to be positively correlated with PIV. Logistic regression analysis showed that hs-CRP and PIV were independently associated with MHT.
conclusionPIV and hs-CRP were independently associated with the presence of MHT. As a simple, inexpensive, and readily available parameter, PIV shows promise in the prediction of patients with MHT in T2DM patients.
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