Evidence map›Paper›PMID 40627302›Full record

ArticleInfection2025

Transitional care after hospitalization for sepsis in Germany- results from the population-based AVENIR cohort study.

Thomas Ruhnke, Josephine Storch, Antje Freytag, Norman Rose, Aurelia Kimmig, Patrik Dröge, Lisa Wedekind, Christian Günster, Ludwig Goldhahn, Enno Swart and 4 more

Abstract read
In one paragraph

Article in Infection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Thomas RuhnkeAOK Research Institute (WIdO), Rosenthaler Strasse 31, 10178, Berlin, Germany.ORCID http://orcid.org/0000-0002-5955-4142
Josephine StorchInstitute of General Practice and Family Medicine, Jena University Hospital, Jena, Germany.ORCID http://orcid.org/0000-0002-4250-0973
Antje FreytagInstitute of General Practice and Family Medicine, Jena University Hospital, Jena, Germany.ORCID http://orcid.org/0000-0001-8288-2729
Norman RoseInstitute of Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany.ORCID http://orcid.org/0000-0002-2908-205X
Aurelia KimmigInstitute of Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany.
Patrik DrögeAOK Research Institute (WIdO), Rosenthaler Strasse 31, 10178, Berlin, Germany.ORCID http://orcid.org/0000-0003-0263-3154
Lisa WedekindInstitute of Medical Statistics, Computer and Data Sciences, Jena University Hospital, Jena, Germany.ORCID http://orcid.org/0000-0001-8291-6298
Christian GünsterAOK Research Institute (WIdO), Rosenthaler Strasse 31, 10178, Berlin, Germany.ORCID http://orcid.org/0000-0003-3085-6259
Ludwig GoldhahnInstitute of Social Medicine and Health Systems Research (ISMHSR), Otto- von-Guericke-University Magdeburg, Magdeburg, Germany.
Enno SwartInstitute of Social Medicine and Health Systems Research (ISMHSR), Otto- von-Guericke-University Magdeburg, Magdeburg, Germany.ORCID http://orcid.org/0000-0002-3286-2217
Mathias W PletzInstitute of Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany.ORCID http://orcid.org/0000-0001-8157-2753
Konrad ReinhartSepsis Foundation, Berlin, Germany.ORCID http://orcid.org/0000-0002-8012-6548
Peter SchlattmannInstitute of Medical Statistics, Computer and Data Sciences, Jena University Hospital, Jena, Germany.ORCID http://orcid.org/0000-0001-7420-7707
Carolin Fleischmann-StruzekInstitute of Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany. carolin.fleischmann-struzek@med.uni-jena.de.ORCID http://orcid.org/0000-0002-1104-3191

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSepsis survivorship is associated with significant long-term morbidity, mortality and health care utilization. Transitional care between inpatient and follow-up care is crucial, but insufficiently understood. We investigated health care utilization in sepsis survivors 90 days post-discharge, comparing translational care during 2016-2019 vs. 2020 in the first year of the pandemic.

methodsThis retrospective cohort study used nationwide health claims data of the "AOK- die Gesundheitskasse". Sepsis patients with inpatient treatment in 2016-2019 were identified using explicit ICD-10 codes for sepsis and codes for organ dysfunction. A second sepsis patient cohort was identified in 2020, which included also explicitly defined sepsis patients as well as patients with COVID-19 and Influenza with evidence of organ dysfunction. Among survivors, health care utilization in the 90 days post-discharge was assessed and first health service provider contacts were visualized using Sankey diagrams.

resultsAmong 234,874 sepsis survivors in 2016-2019, 94.4% were treated by a general practitioner, 47.7% had ≥ 1 hospital readmission and 42.8% of patients had ≥ 1 emergency treatment 90 days post-sepsis. Nearly all patients had prompt health service provider contacts in that time frame, with physicians in the outpatient sector being the most common first and second health service provider contacts. In the 2020 cohort (n = 69,432 survivors), more patients died without follow-up contact. Additionally, the latency to the first and second health service provider contacts were elevated compared to 2016-2019. DISCUSSION: Sepsis survivors receive early, high-frequency follow-up care in the inpatient and outpatient sector. This may be an opportunity to implement early screening for sequelae and targeted therapies.

Indexed as

HospitalizationSepsisTransitional CareAdultAgedAged, 80 and overCohort StudiesCOVID-19FemaleGermanyHumansMaleMiddle AgedPatient Acceptance of Health CareRetrospective StudiesSARS-CoV-2Health care utilizationSankey diagramsSepsisSurvivorTransitional care

Identifiers

PMID40627302
PMCPMC12675533

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.