Evidence map›Paper›PMID 40627255›Full record

Observational studyJournal of clinical monitoring and computing2025

Evaluation of the mitral velocity-time integral changes induced by a passive leg raising test as a marker of fluid responsiveness in critically ill patients.

Younes Aissaoui, Mathieu Jozwiak, Ayoub Bouchama, Hamza Bennjakhoukh, Bassam Bencharfa, Mehdi Didi, Redouane Abouqal, Ayoub Belhadj

Registry-linked trialAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Journal of clinical monitoring and computing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05538637 (Reliability and Accuracy of Mitral Velocity Time-integral Variability With Passive Leg Raising as a Marker of Preload-responsiveness in Patients With Acute Circulatory Failure in the ICU.), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05538637 completednot on this map

Reliability and Accuracy of Mitral Velocity Time-integral Variability With Passive Leg Raising as a Marker of Preload-responsiveness in Patients With Acute Circulatory Failure in the ICU.

TypeobservationalSponsorAvicenna Military HospitalRan2022 to 2024Enrolled50ConditionsPreload-responsivenessArmsEchocardiography
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Younes AissaouiMedical Surgical Intensive Care Unit, Avicenna Military Hospital, Marrakesh, 40160, Morocco. younes.aissaoui@uca.ma.
Mathieu JozwiakService de Médecine Intensive Réanimation, CHU de Nice, Hôpital L'Archet 1, 151 Route Saint Antoine de Ginestière, Nice, 06200, France.
Ayoub BouchamaMedical Surgical Intensive Care Unit, Avicenna Military Hospital, Marrakesh, 40160, Morocco.
Hamza BennjakhoukhMedical Surgical Intensive Care Unit, Avicenna Military Hospital, Marrakesh, 40160, Morocco.
Bassam BencharfaMedical Surgical Intensive Care Unit, Avicenna Military Hospital, Marrakesh, 40160, Morocco.
Mehdi DidiMedical Surgical Intensive Care Unit, Avicenna Military Hospital, Marrakesh, 40160, Morocco.
Redouane AbouqalLaboratory of Biostatistics, Clinical, and Epidemiological Research, Faculty of Medicine and Pharmacy, Mohammed V University, Rabat, Morocco.
Ayoub BelhadjMedical Surgical Intensive Care Unit, Avicenna Military Hospital, Marrakesh, 40160, Morocco.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAssessing fluid responsiveness is crucial in managing critically ill patients. Echocardiography, particularly passive leg raising (PLR)-induced changes in the velocity-time integral of the left ventricular outflow tract (VTI

methodsThis prospective single-center study included septic ICU patients requiring fluid responsiveness assessment. VTI

resultsFifty consecutive patients were included (median age 65 years [IQR: 57-73], APACHE II score 22 [IQR: 18-27]). Septic shock was present in 27 (54%), 21 (42%) were mechanically ventilated, and 23 (46%) were classified as responders. PLR-induced changes in VTI

conclusionPLR-induced changes in VTI

trial registrationNCT05538637.

Indexed as

Critical IllnessFluid TherapyLegMitral ValveAgedBlood Flow VelocityCritical CareEchocardiographyFemaleHemodynamicsHumansIntensive Care UnitsMaleMiddle AgedProspective StudiesRespiration, ArtificialEchocardiographyFluid responsivenessFluidsHemodynamic monitoring

Identifiers

PMID40627255

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.