Evidence map›Paper›PMID 40627203›Full record

ReviewCurrent neurology and neuroscience reports2025

Rehabilitation Strategies for Sleep and Autonomic Symptoms in Parkinson's Disease.

Hikaru Kamo, Koichi Nagaki, Lisa Warren, Alison R Kraus, Michael S Okun, Aparna Wagle Shukla

Abstract readReview
In one paragraph

Review in Current neurology and neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hikaru KamoDepartment of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, USA.
Koichi NagakiDepartment of Neurology, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, 113-8421, Japan.
Lisa WarrenDepartment of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, USA.
Alison R KrausDepartment of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, USA.
Michael S OkunDepartment of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, USA.
Aparna Wagle ShuklaDepartment of Neurology, Fixel Institute for Neurological Diseases, University of Florida, Gainesville, FL, USA. aparna.shukla@neurology.ufl.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewTo evaluate the effectiveness of rehabilitation therapies for managing symptoms of sleep and autonomic dysfunction (cardiovascular, gastrointestinal, urinary and sexual) in Parkinson's disease (PD). The narrative review focuses on recent data drawn from clinical trials, particularly randomized controlled trials, to assess these therapies and the overall quality of the evidence. RECENT

findingsResistance training and aerobic exercises can improve sleep quality in PD. Resistance and aerobic exercises, along with abdominal binders, may help alleviate orthostatic hypotension, though the quality of evidence is not high. Interventions such as expiratory muscle strength training, sensorimotor training, and video-assisted swallowing therapy are beneficial for dysphagia. Pelvic floor muscle training combined with behavioral therapy can potentially mitigate urgency and urge incontinence. Many rehab-based strategies though promising lack sufficient evidence for implementation into clinical practice. The current evidence supports their role in addressing sleep disturbances, orthostatic hypotension and dysphagia. However, the evidence for their effectiveness in treating gastroparesis, constipation, and urinary and sexual dysfunction remains limited.

Indexed as

Autonomic Nervous System DiseasesParkinson DiseaseSleep Wake DisordersExercise TherapyHumansAutonomic dysfunctionCardiovascular dysfunctionGastrointestinal dysfunctionParkinson’s diseaseRehabilitationSexual dysfunctionUrinary dysfunction

Identifiers

PMID40627203
PMCPMC12238090

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.