Evidence map›Paper›PMID 40627087›Full record

ArticleArchives of osteoporosis2025

Comparisons of reference curves for femoral neck geometric parameters between Changsha-Chinese women and women of three ethnic groups in the United States.

Lin Li, Yi Shen, Hong Zhang, Ru-Chun Dai, Ling-Qing Yuan, Zhi-Feng Sheng, Xi-Yu Wu

Abstract readComparative Study
In one paragraph

Article in Archives of osteoporosis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

7 authors.

Lin LiDepartment of Endocrinology and Metabolism, The Affiliated Changsha Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Yi ShenDepartment of Orthopedics, The Second Xiangya Hospital, Central South University, Changsha, China.
Hong ZhangDepartment of Metabolism and Endocrinology, Hunan Provincial Key Laboratory of Metabolic Bone Diseases, National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital of Central South University, Changsha, China.
Ru-Chun DaiDepartment of Metabolism and Endocrinology, Hunan Provincial Key Laboratory of Metabolic Bone Diseases, National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital of Central South University, Changsha, China.
Ling-Qing YuanDepartment of Metabolism and Endocrinology, Hunan Provincial Key Laboratory of Metabolic Bone Diseases, National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital of Central South University, Changsha, China.
Zhi-Feng ShengDepartment of Metabolism and Endocrinology, Hunan Provincial Key Laboratory of Metabolic Bone Diseases, National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital of Central South University, Changsha, China.
Xi-Yu WuDepartment of Metabolism and Endocrinology, Hunan Provincial Key Laboratory of Metabolic Bone Diseases, National Clinical Research Center for Metabolic Diseases, The Second Xiangya Hospital of Central South University, Changsha, China. wuxiyu640@csu.edu.cn.ORCID 0000-0002-4264-8388

Funding

Changsha Natural Science Foundation of China kq2208316Hunan Provincial Natural Science Foundation of China No2023JJ30746National Natural Science Foundation of China 81500685the Project of Hunan Provincial Health Commission D202304077225
6 · The paper itself

Abstract

Factors underlying ethnic differences in the incidence of femoral fractures are not fully understood. Reference curves of femoral neck geometric parameters (FNGPS) between Changsha-Chinese women and three United States (US) ethnic groups of women varied by ethnicity, age, and measurement parameters. Further investigations might better explain fracture-rate differences. PURPOSE: Osteoporotic fractures are associated with race, and the risk of femoral neck fractures is associated with FNGPs. We compared age-related FNGPs of Changsha-Chinese women with those of three ethnic groups of women in the US.

methodsData on 4236 Changsha-Chinese women and non-Hispanic Whites (NHWs), non-Hispanic Blacks (NHBs) and Mexican women (aged 20-91 years) from a laboratory database and research literature, were analyzed to measure their FNGPs: outer diameter (OD), cross-sectional area (CSA), averaged cortical thickness (ACT), endocortical diameter (ED), buckling ratio (BR), section modulus (SM), and cross-sectional moment of inertia (CSMI).

resultsThe overall means of the OD, ED, SM, and CSMI of the Changsha-Chinese women were significantly lower than those of the NHWs. Their CSA, ACT, SM, and CSMI were significantly lower than that of the NHBs and the age-related reference curves of their CSA, ACT, SM, and CSMI were significantly lower than those of the NHWs, NHBs, and Mexican women. Their OD and ED reference curves were significantly lower than those of the NHWs and NHBs; their OD, CSA, and ACT reference curves were lower than those of the NHWs; and their CSA, ACT, and SM were significantly lower than those of the NHBs. However, their buckling ratio (BR) reference curve was significantly higher than that of the NHWs, NHBs, and Mexican women in the US.

conclusionEthnic differences in the FNGPs of Changsha-Chinese women and US ethnic groups may explain differences in hip-fracture rates among different ethnic groups.

Indexed as

Femur NeckAdultAgedAged, 80 and overBlack or African AmericanChinaEast Asian PeopleFemaleFemoral Neck FracturesHumansMiddle AgedNorth American PeopleReference ValuesUnited StatesWhiteYoung AdultEthnic differenceFemoral neck fractureFemoral neck geometric parameterReference curve

Identifiers

PMID40627087
PMCPMC12238157

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