Evidence map›Paper›PMID 40627074›Full record

ArticleAnnals of intensive care2025

Platelet transfusion practice in the intensive care unit: the Nine-I international platelet transfusion survey.

Lene Russell, Elie Azoulay, Carl Thomas Anthon, Frédéric Pène, Padmastuti Akella, Asma Mabrouki, Kathryn Puxty, Lene Bjerregaard Nielsen, Jo Bønding Andreasen, Thomas Kander and 16 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of intensive care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Lene RussellDepartment of Intensive Care, Copenhagen University Hospital Gentofte, Gentofte Hospitalsvej 1, 2900, Hellerup, Denmark. Lene.russell@mail.dk.ORCID http://orcid.org/0000-0001-7352-8728
Elie AzoulayMédecine Intensive & Réanimation, Groupe Famiréa, Hôpital Saint-Louis, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France.
Carl Thomas AnthonDepartment of Intensive Care, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark.
Frédéric PèneMédecine Intensive & Réanimation, Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Institut Cochin, INSERM U1016, CNRS UMR8104, Université Paris Cité, Paris, France.
Padmastuti AkellaDivision of Pulmonary, Critical Care and Sleep Medicine, University of South Florida, Tampa, FL, USA.
Asma MabroukiMédecine Intensive & Réanimation, Groupe Famiréa, Hôpital Saint-Louis, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France.
Kathryn PuxtyDepartment of Intensive Care, Glasgow Royal Infirmary, Glasgow, UK.
Lene Bjerregaard NielsenDepartment of Anaesthesiology and Intensive Care, Odense University Hospital, Odense, Denmark.
Jo Bønding AndreasenDepartment of Anaesthesia and Intensive Care, Aalborg University Hospital, Aalborg, Denmark.
Thomas KanderDepartment of Intensive and Perioperative Care, Skåne University Hospital, Lund, Sweden.
Fredrik SjövallDepartment of Intensive and Perioperative Care, Skåne University Hospital, Lund, Sweden.
Johanna HästbackaDepartment of Intensive Care, Tampere University Hospital, Wellbeing Services County of Pirkanmaa and Tampere University, Tampere, Finland.
Christine Lodberg HvasDepartment of Anaesthesiology and Intensive Care, Aarhus University Hospital, Aarhus, Denmark.
Andry Van De LouwDivision of Pulmonary and Critical Care, Penn State University College of Medicine, Hershey, PA, USA.
Sanjay ChawlaCritical Care Medicine Service, Department of Anesthesiology and Critical Care Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Philippe R BauerDivision of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN, USA.
Pedro CastroMedical Intensive Care Unit, Hospital Clinic Barcelona, IDIBAPS, University of Barcelona, Barcelona, Spain.
Pedro PovoaDepartment of Intensive Care, Hospital de Sao Francisco Xavierl, ULSLO, Lisbon, Portugal.
Luis CoelhoDepartment of Intensive Care, Hospital de Sao Francisco Xavierl, ULSLO, Lisbon, Portugal.
Sara FernandezMedical Intensive Care Unit, Hospital Clinic Barcelona, IDIBAPS, University of Barcelona, Barcelona, Spain.
Arzu TopeliDepartment of Internal Medicine, Division of Intensive Care, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Andreas Barratt-DueDepartment of Anaesthesia and Intensive Care Medicine, Division of Emergencies and Critical Care, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Caterina BarbaglioDepartment of Transplant Anaesthesia and Intensive Care, Great Metropolitan Hospital Niguarda, Milan, Italy.
Matthias KochanekDepartment I of Internal Medicine, Faculty of Medicine, University of Cologne and University Hospital Cologne, Cologne, Germany.
Ignacio Martin-LoechesDepartment of Intensive Care Medicine, Multidisciplinary Intensive Care Research Organisation (MICRO), St James's Hospital, Dublin, Ireland.
Nancy Kentish-BarnesMédecine Intensive & Réanimation, Groupe Famiréa, Hôpital Saint-Louis, Assistance Publique - Hôpitaux de Paris, Université Paris Cité, Paris, France.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Memorial Sloan-Kettering Cancer Center P30CA008748NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundPlatelet transfusions are frequent in the Intensive Care Unit (ICU), either as prophylaxis against bleeding complications or as treatment for bleeding. The European Society of Intensive Care Medicine guidelines for ICU patients generally recommend not using prophylactic platelet transfusions unless the platelet count falls below 10 × 10

methodsAn online, anonymous survey consisting of 43 items was produced in two languages (French and English) and distributed by investigators in the Nine-I research network to ICU physicians in Europe and the United States of America. The survey evaluated platelet transfusion practices in ICU patients with and without bleeding, the presence of local guidelines, and factors influencing the decisions to transfuse platelets. Only completed surveys were analysed.

resultsWe received 997 surveys completed by ICU physicians. Overall, there was large heterogeneity in platelet transfusion practices between and within countries. In non-bleeding, thrombocytopenic medical ICU patients, most would transfuse prophylactic platelets at a platelet count threshold of 10 × 10

conclusionPlatelet transfusion practice in the ICU is heterogeneous, both between and within countries; guidelines are often not used, and there is often uncertainty about the clinical indication.

Indexed as

Critically illIntensive carePlatelet transfusionsThrombocytopenia

Identifiers

PMID40627074
PMCPMC12237844

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.