Evidence map›Paper›PMID 40627057›Full record

ArticleExtremophiles : life under extreme conditions2025

Structural characteristics and immunomodulatory activity of an exopolysaccharide from Antarctic Pseudoalteromonas sp. LP6-12-2.

Dezhi Wang, Han Li, Yu Zhao, Bailin Cong, Pengying Zhang

Abstract read
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Article in Extremophiles : life under extreme conditions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dezhi Wang *National Glycoengineering Research Center, School of Life Science, Shandong University, Qingdao, 266237, China.
Han Li *National Glycoengineering Research Center, School of Life Science, Shandong University, Qingdao, 266237, China.
Yu ZhaoNational Glycoengineering Research Center, School of Life Science, Shandong University, Qingdao, 266237, China.
Bailin CongMarine Ecology Research Center, First Institute of Oceanography, Ministry of Natural Resources, Qingdao, 266061, China.
Pengying ZhangNational Glycoengineering Research Center, School of Life Science, Shandong University, Qingdao, 266237, China. zhangpy80@sdu.edu.cn.

Funding

the National Key Research and Development Program of China 2023YFC2811402the Natural Science Foundation of Shandong Province ZR2022MC075
6 · The paper itself

Abstract

Natural polysaccharides from microorganisms have various biological activities. However, those from psychrophiles with immunomodulatory properties have rarely been found. In this study, an immunoactive exopolysaccharide was extracted from Antarctic Pseudoalteromonas sp. LP6-12-2 (EPS1-1), which isolated using DEAE-Sepharose Fast Flow, Sephadex G-75, and Sephadex G-100. EPS1-1, with a molecular weight 23.47 kDa, was composed of mannose, glucose, galactose, glucosamine, and galactosamine in the ratio of 83.1:7.2:4.3:4.2:1.2. Furthermore, EPS1-1 was found to have a main chain composed of α-D-Manp (1→2) and side chains composed of α-D-Manp (1→6) by FT-IR, methylation, and NMR analyses. Besides, through the Congo red test and I

Indexed as

Immunologic FactorsPolysaccharides, BacterialPseudoalteromonasAnimalsAntarctic RegionsCytokinesMacrophagesMicePhagocytosisRAW 264.7 CellsCytokinesImmunologic FactorsPolysaccharides, BacterialAntarctic psychrophilesExopolysaccharidesImmunomodulatoryPolysaccharide

Identifiers

PMID40627057

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.