Evidence map›Paper›PMID 40626870›Full record

ReviewImmunity, inflammation and disease2025

Disparities in Seasonal Influenza Vaccination in Europe.

Katinka M Giezeman-Smits, Bram Palache, Gerrit A van Essen, Miloš Jeseňák, Enrique Castro-Sánchez, Anna Elisabeth Steinberg, Joris van Vugt

Abstract readReview
In one paragraph

Review in Immunity, inflammation and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katinka M Giezeman-SmitsViatris, Turmstrasse 24, Steinhausen, Switzerland.ORCID 0009-0004-2784-9028
Bram PalacheFluPal Consultancy B.V., Bourgondischelaan 33, Amstelveen, the Netherlands.
Gerrit A van EssenDutch Influenza Foundation, Paladijnenweg 30, Amersfoort, the Netherlands.
Miloš JeseňákComenius University in Bratislava, University Hospital in Martin, Slovakia.
Enrique Castro-SánchezBrunel University London, College of Business, Arts and Social Sciences, Uxbridge, UK.
Anna Elisabeth SteinbergViatris, Benzstraße 1, Bad Homburg vor der Höhe, Germany.
Joris van VugtViatris, Krijgsman 20, Amstelveen, the Netherlands.

Funding

The publication of this article was funded by Viatris.
6 · The paper itself

Abstract

backgroundSeasonal influenza remains a major public health challenge in Europe, associated with high morbidity, mortality, and socioeconomic burden. Despite the proven efficacy and cost-effectiveness of vaccination, coverage rates vary substantially across European countries and population groups, often falling short of the World Health Organization's target of 75% for older adults.

objectiveThis narrative review aims to identify and explore disparities in seasonal influenza vaccination coverage across European countries and among different population subgroups. It also seeks to examine the underlying causes of these disparities and propose actionable strategies to improve equity in vaccine uptake.

methodsA literature search was conducted using the PubMed database for English-language articles published within the last 5 years. Keywords included: comorbidity, disparity, Europe, inequality, influenza, knowledge, ethnic disparity, seasonal influenza vaccination, socioeconomic disparity, vaccination coverage, and vaccine hesitancy. Additional references were identified from the retrieved articles.

resultsWidespread disparities in influenza vaccination were observed across various demographic and professional groups. These included disparities by geographic location, ethnicity, socioeconomic status, sex and gender, age, comorbidities, and occupation-particularly among healthcare professionals. Contributing factors included limited knowledge or education, negative attitudes or behaviors toward vaccination, vaccine hesitancy and fatigue, and restricted access to vaccination services. Structural barriers and institutional trust issues also played key roles.

conclusionsAddressing disparities in influenza vaccination coverage in Europe requires multi-level, stakeholder-specific strategies. These should include education campaigns, improved access through alternative delivery settings (e.g., pharmacies, schools), targeted communication to high-risk and underserved populations, and systemic changes to support healthcare providers. Tackling these issues will help reduce preventable morbidity and mortality, enhance herd immunity, and foster healthier ageing across European populations.

Indexed as

Healthcare DisparitiesInfluenza, HumanInfluenza VaccinesVaccinationEuropeHumansSeasonsSocioeconomic FactorsVaccination CoverageInfluenza Vaccinescomorbidityethnic disparityinequalityinfluenzaseasonal influenza vaccinationvaccine accessvaccine hesitancy

Identifiers

PMID40626870
PMCPMC12235978

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.