Evidence map›Paper›PMID 40626860›Full record

ArticleeLife2025

Function and firing of the

Bastien Casu, Joseph W Sallmen, Peter E Haas, Govind Chandra, Pavel Afanasyev, Jingwei Xu, Martin Pilhofer, Susan Schlimpert

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Bastien CasuDepartment of Biology, Institute of Molecular Biology & Biophysics, Eidgenössische Technische Hochschule Zürich, Zurich, Switzerland.ORCID https://orcid.org/0000-0003-3508-6804
Joseph W SallmenJohn Innes Centre, Department of Molecular Microbiology, Norwich Research Park, Norwich, United Kingdom.
Peter E HaasDepartment of Biology, Institute of Molecular Biology & Biophysics, Eidgenössische Technische Hochschule Zürich, Zurich, Switzerland.
Govind ChandraJohn Innes Centre, Department of Molecular Microbiology, Norwich Research Park, Norwich, United Kingdom.ORCID https://orcid.org/0000-0002-7882-6676
Pavel AfanasyevCryo-EM Knowledge Hub, Eidgenössische Technische Hochschule Zürich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-6353-6895
Jingwei XuDepartment of Biology, Institute of Molecular Biology & Biophysics, Eidgenössische Technische Hochschule Zürich, Zurich, Switzerland.
Martin PilhoferDepartment of Biology, Institute of Molecular Biology & Biophysics, Eidgenössische Technische Hochschule Zürich, Zurich, Switzerland.ORCID https://orcid.org/0000-0002-3649-3340
Susan SchlimpertJohn Innes Centre, Department of Molecular Microbiology, Norwich Research Park, Norwich, United Kingdom.ORCID https://orcid.org/0000-0001-6364-8056

Funding

Biotechnology and Biological Sciences Research Council BB/T015349/1Biotechnology and Biological Sciences Research Council BB/X01097X/1European Research Council 10.3030/679209Royal Society URF\R1\180075Royal Society URF\R\231009Swiss National Science Foundation 31003A_179255/310030_212592
6 · The paper itself

Abstract

Bacterial contractile injection systems (CIS) are phage tail-like macromolecular complexes that mediate cell-cell interactions by injecting effector proteins into target cells. CIS from

Indexed as

Bacterial ProteinsMembrane ProteinsStreptomyces coelicolorCell MembraneCryoelectron MicroscopyBacterial ProteinsMembrane Proteinsbacterial developmentcontractile injection systemsinfectious diseasemicrobiologymulticellularityphage tail-like structuresregulated cell deathStreptomycesstreptomyces coelicolor

Identifiers

PMID40626860
PMCPMC12237407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.