ArticleThe Laryngoscope2025
Investigating Airway Symptoms in Eosinophilic Esophagitis (EoE).
Article in The Laryngoscope, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Eosinophilic esophagitis: An aerodigestive perspective.Journal of pediatric gastroenterology and nutrition · 2026Review
- The Relationship Between Eosinophilic Esophagitis and Laryngeal Manifestations: Pathophysiology, Clinical Overlap, and Diagnostic Challenges.Journal of clinical medicine · 2026Review
- Investigating Airway Symptoms in Eosinophilic Esophagitis (EoE).The Laryngoscope · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesDiagnostic delay of eosinophilic esophagitis (EoE) is significant, and efforts are needed to raise awareness and reduce prolonged symptoms and complications. Airway and swallowing symptoms often overlap, especially in children, complicating diagnosis and increasing delays. This study aims to report the range of airway presentations in pediatric EoE patients and identify independent predictors of an EoE diagnosis in patients with aerodigestive symptoms.
methodsWe conducted a retrospective case-control study of pediatric patients < 7 years with histologically confirmed EoE managed in an aerodigestive clinic at a tertiary pediatric center. Variables included demographics, atopic comorbidities, risk factors, airway and dysphagia symptoms, and adaptive eating behaviors. EoE cases were age-matched to controls with aerodigestive issues and no EoE. Multivariate regression analysis identified independent predictors of EoE.
resultsFifty EoE patients were included, along with 50 controls. The mean age was 2.4 years, with 70% male. Common EoE symptoms included solid food dysphagia (62%), food pocketing (62%), and self-reported food allergies (72%). Airway symptoms included chronic cough (38%) and choking (32%). Multivariate analysis identified food allergy (OR 15.7) and food pocketing (OR 11.81) as independent predictors, while dysphagia with liquids (OR 0.058) and recurrent pneumonia (OR 0.022) were negative predictors.
conclusionAirway symptoms in pediatric EoE can overlap with other conditions, complicating diagnosis. Key features such as adaptive eating behavior and food allergies should raise suspicion for EoE. LEVEL OF EVIDENCE: 3:
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.