Evidence map›Paper›PMID 40626690›Full record

ArticleJournal of virology2025

Epstein-Barr virus-infected tonsillar marginal zone B cells

Charles Torgbor, David A Thorley-Lawson, Ann M Moormann

Abstract read
In one paragraph

Article in Journal of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. A tonsil organoid model reveals Epstein-Barr virus-infected germinal center B cell states during primary infection.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Charles TorgborTufts University School of Medicine, Boston, Massachusetts, USA.ORCID 0000-0002-7522-8216
David A Thorley-Lawson *Tufts University School of Medicine, Boston, Massachusetts, USA.
Ann M Moormann *Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.ORCID 0000-0003-1113-2829

Funding

HOST IMMUNITY TO EBV INFECTION IN VITRO AND IN VIVOR01AI018757 · NIAID · TUFTS UNIVERSITY BOSTON · PI POLTORAK, ALEXANDER · 1985 to 2017
$6.7M
Impact of malaria on shaping immunity to EBV in the etiology of Burkitt lymphomaR01CA189806 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MOORMANN, ANN M · 2014 to 2024
$5.7M
NCI NIH HHS R01 CA189806NIAID NIH HHS R01 AI018757
6 · The paper itself

Abstract

The germinal center model (GCM) of Epstein-Barr virus (EBV) persistence in humans proposes that EBV infects and drives naïve B cells through the GC to establish a quiescent lifelong persistent infection in memory B cells. EBV causes several cancers, and the normal

Indexed as

B-LymphocytesEpstein-Barr Virus InfectionsHerpesvirus 4, HumanLymphoma, B-CellPalatine TonsilGerminal CenterHumansViral Matrix ProteinsEBV-associated membrane antigen, Epstein-Barr virusViral Matrix ProteinsB-cell lymphomaB cellsEpstein-Barr virus

Identifiers

PMID40626690
PMCPMC12363164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.