Observational studyActa ophthalmologica2026
Muscle tendon elongation with bovine pericardium (Tutopatch®) in patients with Graves' orbitopathy; a prospective, observational, multicentre study.
Observational study in Acta ophthalmologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- The Tutopatch® assisted surgery for complex strabismus study: TASCS-study.Acta ophthalmologica · 2026Article
- Muscle tendon elongation with bovine pericardium (Tutopatch®) in patients with Graves' orbitopathy; a prospective, observational, multicentre study.Acta ophthalmologica · 2026Observational
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Authors and funding
8 authors.
Funding
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Abstract
purposePatients with severe ocular motility restriction and/or large angle strabismus due to Graves' orbitopathy (GO) cannot be adequately addressed with conventional strabismus surgery using large muscle recessions. Muscle tendon elongation surgery, using a spacer of bovine pericardium (Tutopatch®) has emerged as a valuable alternative. The purpose of this study was to assess the long-term outcome of muscle elongation surgery in patients with GO.
methodsA prospective observational cohort study in three University centres was conducted. All GO patients requiring strabismus surgery with elongation material of one or more rectus muscles were included. One week preoperatively and 3 and 6 months postoperatively, ophthalmic and orthoptic examinations were performed.
resultsThirty-five patients were enrolled in the study. The mean length of spacer used was 8.2 mm (range 4-13 mm). Tendon elongation was performed on 15 inferior rectus muscles, 33 medial rectus muscles and 9 superior rectus muscles. The field of BSV improved from 0 points [IQR 0-0] preoperatively to 80 points [IQR 6-92] postoperatively (p < 0.001). QoL for functional questions changed from 47 points [IQR 31-63] preoperatively to 78 points [IQR 73-100] postoperatively (p = <0.001). HADS level of anxiety and depression remained below the cut-off score of 15 points (preoperative 11.5 and postoperative 5.7 points).
conclusionsUsing the muscle tendon elongation technique with Tutopatch® in GO patients with severely restricted strabismus, 3 months after surgery a stable large field of BSV can be achieved with associated improvement of the QoL. It is a safe and effective alternative to large muscle recessions for restricted muscle.
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