Evidence map›Paper›PMID 40626529›Full record

ReviewCurrent protein & peptide science2026

Comprehensive Review of L-Lysine: Chemistry, Occurrence, and Physiological Roles.

Mohd Hashim, Intekhab Alam, Mohammad Ahmad, Badruddeen, Juber Akhtar, Mohammad Irfan Khan, Anas Islam, Shumaila Parveen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current protein & peptide science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohd HashimDepartment of Pharmacy, Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, 226026, India.
Intekhab AlamDepartment of Pharmacy, Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, 226026, India.
Mohammad AhmadDepartment of Pharmacy, Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, 226026, India.
BadruddeenDepartment of Pharmacy, Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, 226026, India.
Juber AkhtarDepartment of Pharmacy, Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, 226026, India.
Mohammad Irfan KhanDepartment of Pharmacy, Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, 226026, India.
Anas IslamDepartment of Pharmacy, Faculty of Pharmacy, Integral University, Lucknow, Uttar Pradesh, 226026, India.
Shumaila ParveenDepartment of Biosciences, Integral University, Lucknow, Uttar Pradesh, 226026, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

L-lysine, an essential amino acid, is indispensable for numerous biological functions, including protein synthesis, collagen crosslinking, mineral absorption, and carnitine biosynthesis. Its biosynthesis occurs via the Diaminopimelate (DAP) pathway in bacteria and plants and the α-aminoadipate (AAA) pathway in fungi and some archaea. Lysine catabolism primarily involves the saccharopine pathway. Lysine deficiencies can lead to connective tissue disorders, impaired fatty acid metabolism, anemia, and protein-energy malnutrition. Commercial production relies predominantly on microbial fermentation using

Indexed as

Lysine2-Aminoadipic AcidAnimalsBacteriaCorynebacterium glutamicumEpigenesis, GeneticHumansPlants2-Aminoadipic AcidLysinesaccharopinebiosynthesisCorynebacterium glutamicumEscherichia coliLysinemetabolic engineeringprotein synthesis

Identifiers

PMID40626529

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.