Evidence map›Paper›PMID 40626292›Full record

ArticlePediatric discovery2025

Clinical analysis of ultrasound-guided microwave ablation for pediatric thyroid nodules- a single center research.

Hongxia Zhang, Mingzhu Yu, Jingyu Chen, Caihui Hu, Yi Tang, Zhenzhen Zhao, Yifei Du, Jian Sun, Jianwu Zhou, Chao Yang and 2 more

Abstract read
In one paragraph

Article in Pediatric discovery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The role and mechanisms of vitamin A in suppressing hepatic stellate cell activation.Apoptosis : an international journal on programmed cell death · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hongxia ZhangDepartment of Surgical Oncology Ministry of Education Key Laboratory of Child Development and Disorders Chongqing Key Laboratory of Pediatrics Children's Hospital of Chongqing Medical University National Clinical Research Center for Child Health and Disorders Chongqing China.ORCID https://orcid.org/0009-0006-0905-4154
Mingzhu YuDepartment of Ultrasound Children's Hospital of Chongqing Medical University Chongqing China.
Jingyu ChenDepartment of Ultrasound Children's Hospital of Chongqing Medical University Chongqing China.
Caihui HuDepartment of Ultrasound Children's Hospital of Chongqing Medical University Chongqing China.
Yi TangDepartment of Ultrasound Children's Hospital of Chongqing Medical University Chongqing China.
Zhenzhen ZhaoDepartment of Surgical Oncology Ministry of Education Key Laboratory of Child Development and Disorders Chongqing Key Laboratory of Pediatrics Children's Hospital of Chongqing Medical University National Clinical Research Center for Child Health and Disorders Chongqing China.
Yifei DuDepartment of Surgical Oncology Ministry of Education Key Laboratory of Child Development and Disorders Chongqing Key Laboratory of Pediatrics Children's Hospital of Chongqing Medical University National Clinical Research Center for Child Health and Disorders Chongqing China.
Jian SunDepartment of Surgical Oncology Ministry of Education Key Laboratory of Child Development and Disorders Chongqing Key Laboratory of Pediatrics Children's Hospital of Chongqing Medical University National Clinical Research Center for Child Health and Disorders Chongqing China.
Jianwu ZhouDepartment of Surgical Oncology Ministry of Education Key Laboratory of Child Development and Disorders Chongqing Key Laboratory of Pediatrics Children's Hospital of Chongqing Medical University National Clinical Research Center for Child Health and Disorders Chongqing China.
Chao YangDepartment of Surgical Oncology Ministry of Education Key Laboratory of Child Development and Disorders Chongqing Key Laboratory of Pediatrics Children's Hospital of Chongqing Medical University National Clinical Research Center for Child Health and Disorders Chongqing China.
Xiaobin DengDepartment of Surgical Oncology Ministry of Education Key Laboratory of Child Development and Disorders Chongqing Key Laboratory of Pediatrics Children's Hospital of Chongqing Medical University National Clinical Research Center for Child Health and Disorders Chongqing China.
Xiangru KongDepartment of Surgical Oncology Ministry of Education Key Laboratory of Child Development and Disorders Chongqing Key Laboratory of Pediatrics Children's Hospital of Chongqing Medical University National Clinical Research Center for Child Health and Disorders Chongqing China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To provide a new minimally invasive treatment for children with benign thyroid nodules, and to provide clinical data for applying microwave ablation (MWA) to children. A retrospective analysis was conducted on the clinical data of 21 pediatric patients with benign thyroid nodules who underwent ultrasound-guided MWA at the Children's Hospital affiliated with Chongqing Medical University from July 2022 to August 2023. The safety, clinical efficacy, volume reduction ratio and prognostic value of the treatment were evaluated. The participants were followed for at least 4 months (median 7 months, range 4-16 months). The average (range) ablation time for the 21 patients was only(233.90 ± 184.97) (40-660)seconds, with intraoperative bleeding less than 0.5 mL. No complications such as hoarseness, seizures or coughing during drinking water were observed after ablation treatment. All the participants' hormone reflecting thyroid function remained in the normal ranges after treatment. Besides, these hormones at 12 h after surgery and 1 month after surgery were not statistically different from those before surgery. Immediate postoperative ultrasound imaging showed a significant decrease in volume of benign thyroid nodules, the volume of nodules at 1 month postoperatively (M, 1.39), and the volume of nodules at 4 months postoperatively (M, 0.40) significantly smaller than that before surgery (M, 4.94). Ultrasound-guided MWA is a new option for the treatment of benign thyroid nodules in children, with advantages such as minimal invasiveness, good clinical effect, high safety, little damage to thyroid function, short operation time, less intraoperative bleeding, low pain sensation and aesthetic appearance.

Indexed as

benign thyroid noduleschildrenmicrowave ablationthyroid hormones

Identifiers

PMID40626292
PMCPMC12118115

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.