ReviewSmart molecules : open access2024
Tissue-seeking dyes for in vivo applications.
Review in Smart molecules : open access, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed.
- More Than a Glow: How Cyanine Dyes Shape Tracer Pharmacokinetics.Angewandte Chemie (International ed. in English) · 2026Review
- Review: structural determinants of organic dyes for controlling biological clearance pathways.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026Review
- Advances in near-infrared fluorescent probes for the tumor microenvironment.Journal of translational medicine · 2026Review
- Trinuclear Heptamethine Dyes for Shortwave Infrared In Vivo Imaging.Angewandte Chemie (International ed. in English) · 2026Article
- Bulky Group Shaping Cyanine as an Efficient Photosensitizer: A Photo-Inducer for Photodynamic Immunotherapy.JACS Au · 2025Article
- A β-galactosidase activated near-infrared fluorescent probe for tracking cellular senescence in vitro and in vivo.Smart molecules : open access · 2025Article
- Tissue-seeking dyes for in vivo applications.Smart molecules : open access · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In vivo optical imaging has become an invaluable tool for visualizing and monitoring biological processes in living organisms. A key component of these imaging techniques is the use of fluorescent dyes that can selectively target and label specific tissues or cell types. This review provides an overview of the current state of tissue-seeking dyes for in vivo applications. We discuss the design principles and chemical structures of dyes that have been developed to target various tissues of interest, including tumors, nerves, bones, vasculatures, and other tissues. The review covers the photophysical properties, targeting mechanisms, and in vivo performance of these dyes. Particular emphasis is placed on dyes that have demonstrated clinical translation or have high potential for future clinical use. The review also examines the challenges and considerations in developing effective tissue-seeking dyes, such as achieving high specificity, overcoming biological barriers and minimizing toxicity. Finally, we highlight emerging trends and future directions in the field, including the integration of tissue-seeking dyes with advanced imaging modalities and theranostic applications. Overall, this review provides a focused summary of the current landscape of tissue-seeking dyes and their pivotal role in advancing in vivo optical imaging and its biomedical applications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.