Evidence map›Paper›PMID 40626273›Full record

ReviewSmart molecules : open access2024

Recent advances in dual response molecular probes for biothiols.

Master Mwafulirwa, Khamis Abdalla, Wenhai Bian, Hongbei Wei, Liren Xu, Wanyi Yu, Zhang Hui, Qi Yang, Xiaolong Sun

Abstract readReview
In one paragraph

Review in Smart molecules : open access, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Master MwafulirwaThe Key Laboratory of Biomedical Information Engineering of Ministry of Education School of Life Science and Technology Xi'an Jiaotong University Xi'an China.
Khamis AbdallaThe Key Laboratory of Biomedical Information Engineering of Ministry of Education School of Life Science and Technology Xi'an Jiaotong University Xi'an China.
Wenhai BianThe Key Laboratory of Biomedical Information Engineering of Ministry of Education School of Life Science and Technology Xi'an Jiaotong University Xi'an China.
Hongbei WeiThe Key Laboratory of Biomedical Information Engineering of Ministry of Education School of Life Science and Technology Xi'an Jiaotong University Xi'an China.
Liren XuThe Key Laboratory of Biomedical Information Engineering of Ministry of Education School of Life Science and Technology Xi'an Jiaotong University Xi'an China.
Wanyi YuThe Key Laboratory of Biomedical Information Engineering of Ministry of Education School of Life Science and Technology Xi'an Jiaotong University Xi'an China.
Zhang HuiThe Key Laboratory of Biomedical Information Engineering of Ministry of Education School of Life Science and Technology Xi'an Jiaotong University Xi'an China.
Qi YangThe Key Laboratory of Biomedical Information Engineering of Ministry of Education School of Life Science and Technology Xi'an Jiaotong University Xi'an China.
Xiaolong SunThe Key Laboratory of Biomedical Information Engineering of Ministry of Education School of Life Science and Technology Xi'an Jiaotong University Xi'an China.ORCID https://orcid.org/0000-0003-4003-6924

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The detection of biothiols such as cysteine (Cys), homocysteine (Hcy), and glutathione (GSH) are critical for understanding their roles in biology and their involvement in various physiological and pathological processes. Recently, significant progress has been made in constructing fluorescent probes capable of detecting and visualizing biothiols. This review provides an in-depth look at the latest advancements in simultaneous and selective molecular probes, focusing on developments over the last 5 years. We examine design techniques, sensing mechanisms, and imaging methods to assess their effectiveness and responsiveness to thiols. Additionally, we discuss the prevailing challenges and offer recommendations to address them.

Indexed as

biothiolsdiscriminative responsedual‐mode imagingfluorescent probefluorogenic detection

Identifiers

PMID40626273
PMCPMC12118221

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.