Evidence map›Paper›PMID 40626247›Full record

ReviewPediatric discovery2024

MicroRNAs as potential biomarkers for monitoring of acquired sensorineural hearing loss.

Yaqin Hu, Hongjiang Chen, Xiaoqing Zhou, Xiaoqin Luo, Zailan Tu, Jing Ke, Wei Yuan

Abstract readReview
In one paragraph

Review in Pediatric discovery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yaqin HuChongqing Medical University Chongqing China.ORCID https://orcid.org/0000-0002-9328-7201
Hongjiang ChenChongqing Medical University Chongqing China.
Xiaoqing ZhouDepartment of Otolaryngology Chongqing General Hospital Chongqing China.
Xiaoqin LuoDepartment of Otolaryngology Chongqing General Hospital Chongqing China.
Zailan TuChongqing Medical University Chongqing China.
Jing KeDepartment of Otolaryngology Chongqing General Hospital Chongqing China.
Wei YuanChongqing Medical University Chongqing China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Presbyacusis, sudden sensorineural hearing loss (SNHL), noise-induced hearing loss, and drug-induced deafness are the most common types of acquired SNHL. At present, the diagnosis of these hearing disorders is mainly based on the medical history and audiological examination. Due to the lack of diagnostic biomarkers, diagnosis of acquired sensorineural hearing loss is difficult. Previous studies have suggested that microRNAs (miRNAs) serve essential roles in pathophysiological processes, and they are stable, tissue enriched, and could be determined in a quantitative manner. Therefore, they could be potential noninvasive biomarkers for acquired SNHL. This review provided a comprehensive overview of the similarities and differences in altered circulating miRNAs (cimiRNAs) (plasma, serum, whole blood, and perilymph) in various disorders, and highlighted the regulatory functions of cimiRNAs on the development, monitoring and prognosis of the four most common types of acquired SNHL.

Indexed as

biomarkerscirculating miRNAsdeafnesssensorineural hearing loss

Identifiers

PMID40626247
PMCPMC12118228

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.