ArticleHealth science reports2025
Mpox Outbreak: A Call for Urgent Action and Improved Response Strategies.
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Editorial: Epidemiological investigations of zoonotic viruses and research on drugs and vaccines.Frontiers in veterinary science · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The resurgence of mpox presents a significant global public health challenge, especially in non-endemic regions. Following its initial global spread in 2022, the current outbreak is driven by a newly emerged Clade I, exhibiting atypical clinical manifestations and altered transmission patterns. These changes, coupled with limited immunity in younger populations due to the absence of smallpox vaccination, underscore the severity. As of June 2024, nearly 100,000 cases have been documented worldwide, with Africa experiencing the majority of new cases, highlighting critical gaps in global health preparedness. Methodology: This article provides an updated analysis of recent mpox cases, exploring the distinct epidemiological and clinical challenges of the current outbreak. It examines transmission patterns, affected demographics, and obstacles like underreporting to understand the evolving crisis. Results: The current outbreak is primarily centered in the Democratic Republic of Congo but poses global transmission risks. The dominance of the more severe Clade I and a significant shift towards human-to-human transmission, predominantly through sexual contact (83.3% of cases in males aged 29-41), characterize its epidemiology. Inadequate surveillance and underreporting, particularly in low-resource settings, obscure the true extent of the outbreak. The analysis reveals the urgent need for a coordinated, multisectoral global response. Conclusion: Mpox outbreak underscores critical deficiencies in global health preparedness. An effective response requires an evidence-based, coordinated approach, integrating technical, social, and financial resources internationally and locally. Key recommendations include strengthening surveillance, improving diagnostics, enhancing equitable vaccine accessibility, and implementing robust anti-stigma initiatives at all levels. An inclusive, multisectoral collaboration between governments, international organizations, and community leaders is crucial to mitigate the public health, social, and economic impacts of this persistent outbreak.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.