Evidence map›Paper›PMID 40626156›Full record

SynthesisFrontiers in public health2025

Artificial intelligence in early warning systems for infectious disease surveillance: a systematic review.

Ismael Villanueva-Miranda, Guanghua Xiao, Yang Xie

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Drug sales data for gastrointestinal infections surveillance: a systematic review up to 2025.Archives of public health = Archives belges de sante publique · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ismael Villanueva-MirandaDepartment of Health Data Science and Biostatistics, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Guanghua XiaoDepartment of Health Data Science and Biostatistics, University of Texas Southwestern Medical Center, Dallas, TX, United States.
Yang XieDepartment of Health Data Science and Biostatistics, University of Texas Southwestern Medical Center, Dallas, TX, United States.

Funding

Developing novel algorithms for spatial molecular profiling technologiesR01GM141519 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI XIAO, GUANGHUA · 2021 to 2024
$1.4M
NIGMS NIH HHS R01 GM141519
6 · The paper itself

Abstract

Introduction: Infectious diseases pose a significant global health threat, exacerbated by factors like globalization and climate change. Artificial intelligence (AI) offers promising tools to enhance crucial early warning systems (EWS) for disease surveillance. This systematic review evaluates the current landscape of AI applications in EWS, identifying key techniques, data sources, benefits, and challenges. Methods: Following PRISMA guidelines, a systematic search of Semantic Scholar (2018-onward) was conducted. After screening 600 records and removing duplicates and non-relevant articles, the search yielded 67 relevant studies for review. Results: Key findings reveal the prevalent use of machine learning (ML), deep learning (DL), and natural language processing (NLP), which often integrate diverse data sources (e.g., epidemiological, web, climate, wastewater). The major benefits identified include earlier outbreak detection and improved prediction accuracy. However, significant challenges persist regarding data quality and bias, model transparency (the "black box" issue), system integration difficulties, and ethical considerations such as privacy and equity. Discussion: AI demonstrates considerable potential to strengthen infectious disease EWS. Realizing this potential, however, requires concerted efforts to address data limitations, enhance model explainability, ensure ethical implementation, improve infrastructure, and foster collaboration between AI developers and public health experts.

Indexed as

Artificial IntelligenceCommunicable DiseasesPopulation SurveillanceDeep LearningDisease OutbreaksHumansMachine LearningNatural Language Processingartificial intelligencedisease surveillanceearly warning system (EWS)infectious diseasepublic healthsystematic review

Identifiers

PMID40626156
PMCPMC12230060

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.