ArticlePediatric discovery2023
The clinical condition rather than cerebrospinal fluid levels may guide the optimal duration of antimicrobial therapy among neonates with bacterial meningitis: A single-center retrospective study.
Article in Pediatric discovery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neonatal bacterial meningitis is serious and accounts for high morbidity and mortality in developing countries, but the duration of antimicrobial treatment is not well established. Cerebrospinal fluid (CSF) levels are important factors for diagnosing and monitoring the occurrence and development of bacterial meningitis. In this study, we aimed to compare the clinical characteristics and outcomes of neonatal bacterial meningitis with normal CSF and abnormal CSF at discharge. We enrolled neonates with bacterial meningitis who were admitted to the neonatology department of the Children's Hospital of Chongqing Medical University between August 1, 2019 and January 1, 2021. The children's clinical data, laboratory data, and outcomes were recorded and analyzed. Fifty-five neonates met the inclusion criteria in our study. Other than CSF protein levels, there was no significant difference in clinical symptoms, blood levels (white blood cell [WBC] count, neutrophils, platelets, C-reactive protein, and procalcitonin), CSF WBC counts at admission and discharge, duration of antibiotics, or hospital stays between the two groups (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.