ReviewRSC advances2025
Multifunctional resin-matrix ceramic: synergistic mechanical-biological optimization and novel strategies for translational research.
Review in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The advancement of dental materials has established resin-zirconia RMC (resin-matrix ceramic) as a pivotal innovation in restorative dentistry, combining zirconia's mechanical strength with resin's elasticity to overcome the limitations of traditional systems. Conventional materials often compromise tooth integrity due to elastic modulus mismatch and cytotoxic monomer release, whereas resin-zirconia RMC (resin-matrix ceramic) achieve stress distribution aligned with natural dentition while enhancing biocompatibility. This review explores their design strategies, including nano-zirconia reinforcement, polymer-ceramic network optimization, and surface functionalization, which collectively improve wear resistance, aging stability, and antibacterial efficacy. Clinically, these composites demonstrate exceptional performance, with long-term success and minimal wear under cyclic loading. Mechanistically, they regulate cellular interactions critical to soft tissue healing and bone integration, suppressing inflammatory pathways while promoting osteoblast activity and collagen alignment. Despite these advancements, challenges such as the long-term biocompatibility of wear particles and processing complexity require further investigation. By integrating material science, cell biology, and clinical insights, this work underscores the potential of resin-zirconia RMC (resin-matrix ceramic) to redefine restorative dentistry through harmonized mechanical and biological functionality.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.