ReviewSmart molecules : open access2024
Recent advances in self-immobilizing fluorescent probes for in vivo imaging.
Review in Smart molecules : open access, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Rational design of a lipophilic β-galactosidase-responsive near-infrared probe for in vivo imaging of cellular senescence.Smart molecules : open access · 2026Article
- Enzyme-Activatable Fluorogenic Probes: Design Strategies, Biomedical Applications, and Future Perspectives.Journal of the American Chemical Society · 2026Review
- Controlled In Situ Self-Assembly for Pretargeted Tumor Theranostics via Bioorthogonal Activation.Advanced healthcare materials · 2026Article
- An ESIPT-AIE nanosensor for ONOOJournal of nanobiotechnology · 2026Article
- Self-assembled fluorescent nanosensor for ultrafast and field-deployable monitoring of herbicide fomesafen in multiple matrices.Journal of nanobiotechnology · 2026Article
- Recent Advances in Bioconjugation of Aromatic Amino Acid Residues by a Reactivity-Guided Approach.Chemical record (New York, N.Y.) · 2026Review
- Steric confinement-induced emission probe for monitoring protein conformations in live cells.Communications chemistry · 2026Article
- Programmable Multi-State Fluorescence Switching on a Dynamic Molecular System via Sequential Dynamic Covalent Chemistry and Applications.Precision chemistry · 2025Article
- Enzyme-activatable dual-locked fluorescent probe for precision imaging of cutaneous squamous cell carcinoma.Smart molecules : open access · 2025Article
- Recent Advances of Nitrobenzoselenadiazole for Imaging and Therapy.ACS sensors · 2025Review
- A β-galactosidase activated near-infrared fluorescent probe for tracking cellular senescence in vitro and in vivo.Smart molecules : open access · 2025Article
- Fluorescent probes for the visualization of membrane microdomain, deformation, and fusion.Smart molecules : open access · 2025Review
- Recent advances in self-immobilizing fluorescent probes for in vivo imaging.Smart molecules : open access · 2024Review
- Research Progress on Dual-Modal Fluorescence-MRI Molecular Imaging of Molecular Probes in Breast Cancer.Technology in cancer research & treatmentReview
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In situ precise detection of bioactive molecules with high sensitivity and spatiotemporal resolution is essential for studying physiological events and disease diagnosis. The utilization of versatile fluorescent probes in fluorescence imaging offers a powerful tool for in vivo imaging of biomarkers closely associated with pathological conditions. However, the dynamic behavior leading to rapid clearance of small molecule probes from regions of interest severely compromises their potential for precise imaging. Notably, self-immobilizing fluorescent probes that selectively recognize diseased tissues while improving in situ retention and enrichment enable accurate high-fidelity fluorescence imaging. In this review, we aim to summarize the strategies employed for recent advances in the performance and precision of in vivo fluorescence imaging using self-immobilizing techniques. Lastly, we discuss the prospects and potential challenges associated with self-immobilizing fluorescent probes to promote further development and application of more delicate fluorescent probes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.