Evidence map›Paper›PMID 40625903›Full record

ArticleFrontiers in neurology2025

Feasibility and preliminary efficacy of an online home-based functional exercise program for Parkinson's disease: a pilot study.

Hyungwoo Lee, Hunyoung Ha, Heehyun Shin, Byungjun Park, Nyeonju Kang, Kiwon Park, Ryul Kim, Kyeongho Byun

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hyungwoo Lee *Department of Human Movement Science, Incheon National University, Incheon, Republic of Korea.
Hunyoung Ha *Department of Human Movement Science, Incheon National University, Incheon, Republic of Korea.
Heehyun ShinDepartment of Human Movement Science, Incheon National University, Incheon, Republic of Korea.
Byungjun ParkDivision of Sport Science, Sport Science Institute & Health Promotion Center, Incheon National University, Incheon, Republic of Korea.
Nyeonju KangDivision of Sport Science, Sport Science Institute & Health Promotion Center, Incheon National University, Incheon, Republic of Korea.
Kiwon ParkDepartment of Biomedical and Robotics Engineering, Incheon National University, Incheon, Republic of Korea.
Ryul KimDepartment of Neurology, Seoul Metropolitan Government - Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, Republic of Korea.
Kyeongho ByunDivision of Sport Science, Sport Science Institute & Health Promotion Center, Incheon National University, Incheon, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Parkinson's disease (PD) leads to motor and non-motor impairments, contributing to sarcopenia and reduced functional independence. While functional strength exercises can help manage these symptoms, adherence remains challenging, particularly in home-based setting. Objective: This pilot exercise intervention study aimed to evaluate the feasibility and efficacy of an 8-week Online Home-Based Exercise Program (OHEP), which provides easy-to-follow functional strength exercises for PD patients, enabling them perform these exercises safely and effectively at home. Methods: Fifteen patients with early-stage PD (Hoehn and Yahr Stage 1-2) participated in an 8-week exercise intervention, consisting of a 2-week in-person training followed by a 6-week online home-based exercise session using Zoom. The exercise regimen included softball, bodyweight, elastic band, and step box exercises targeting muscle strength, balance, and mobility. Feasibility was assessed through attrition rate, adherence rate, compliance rate, and safety. Efficacy was evaluated by examining changes in motor and non-motor symptoms, body composition, and physical performance. Results: Three participants withdrew from the study, resulting in an attrition rate of 20%. Feasibility was supported by a high adherence rate (median: 91%) and exercise compliance rates exceeding 93% across all exercise types. No adverse events reported. Among clinical outcomes, depressive symptoms significantly improved (Beck Depression Inventory, Conclusion: These findings suggest that a short-term OHEP is feasible and safe intervention for PD patients, with potential benefits in improving depressive symptoms and physical function. However, further randomized controlled long-term studies are needed to better delineate the effects of this intervention in the management of PD. Clinical trial registration: https://cris.nih.go.kr, Identifier: KCT0008302.

Indexed as

exercise compliance ratefeasibilityonline home-based exerciseParkinson's diseasestrength training

Identifiers

PMID40625903
PMCPMC12229864

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.