Evidence map›Paper›PMID 40625876›Full record

ReviewFrontiers in plant science2025

The clues offered by SNAREs on the vacuoles of plants and animals.

Fabrizio Barozzi, Miguel Sampaio, Cláudia Pereira, Gian Pietro Di Sansebastiano

Abstract readReview
In one paragraph

Review in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Frontiers in plant science · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fabrizio BarozziDiSTeBA (Department of Biological and Environmental Sciences and Technologies), University of Salento, Lecce, Italy.
Miguel SampaioGreenUPorto - Sustainable Agrifood Production Research Centre/Inov4Agro, Department of Biology, Faculty of Sciences, University of Porto, Porto, Portugal.
Cláudia PereiraGreenUPorto - Sustainable Agrifood Production Research Centre/Inov4Agro, Department of Biology, Faculty of Sciences, University of Porto, Porto, Portugal.
Gian Pietro Di SansebastianoDiSTeBA (Department of Biological and Environmental Sciences and Technologies), University of Salento, Lecce, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vacuoles and lysosome-related organelles (LROs) are essential compartments in eukaryotic cells playing crucial roles in storage, degradation, signaling, and homeostasis. Despite their functional similarities, these organelles have traditionally been studied in isolation within plant and animal cell biology. This review bridges these disciplines by exploring the molecular parallels between plant vacuoles and animal LROs, with a particular emphasis on the SNARE (Soluble N-ethylmaleimide-sensitive factor Attachment Protein Receptor) protein family, which governs membrane fusion and trafficking. SNARE complexes orchestrate intracellular transport ensuring the correct delivery of cargo to vacuoles and LROs. By analyzing SNARE homologs and their interactions across kingdoms, we highlight conserved mechanisms that regulate organelle biogenesis, remodeling, and function. This comparative approach not only advances our understanding of cellular compartmentalization but also sheds light on potential applications in biotechnology, stress adaptation, and human disease research. Integrating knowledge from plant and animal systems offers a powerful framework for discovering novel regulatory pathways in membrane trafficking and cellular homeostasis.

Indexed as

adipocyteslipid dropletsLROsmelanocytesSNAREsvacuoles

Identifiers

PMID40625876
PMCPMC12230059

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.