Evidence map›Paper›PMID 40625821›Full record

ArticleARYA atherosclerosis2025

Association between egg consumption and major and minor ischemia changes on electrocardiogram: A population-based study.

Najmeh Seifi, Sara Saffar Soflaei, Muhammad Islampanah, Hossein Hatamzadeh, Bahareh Payami, Mahsa Ammarlou, Farnaz Farrokhzadeh, Habibollah Esmaily, Sara Yousefian, Helia Rezaeifard and 3 more

Abstract read
In one paragraph

Article in ARYA atherosclerosis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Najmeh SeifiDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Sara Saffar SoflaeiInternational UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.
Muhammad IslampanahStudent Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Hossein HatamzadehDepartment of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Bahareh PayamiMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Mahsa AmmarlouStudent Research Committee, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Farnaz FarrokhzadehMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Habibollah EsmailyMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Sara YousefianInternational UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.
Helia RezaeifardDepartment of Biostatistics, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran; Social Determinants of Health Research center, Mashhad University of Medical Sciences, Mashhad, Iran.
Gordon A FernsDivision of Medical Education, Brighton & Sussex Medical School, Falmer, Brighton, Sussex, UK.
Mohsen MoohebatiMetabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Majid Ghayour-MobarhanInternational UNESCO Center for Health-Related Basic Sciences and Human Nutrition, Mashhad University of Medical Sciences, Mashhad, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEggs, while nutrient-rich, have high cholesterol content. The link between egg consumption and cardiovascular disease (CVD) remains debated. This study investigates how egg intake correlates with minor and major electrocardiogram (ECG) abnormalities, which serve as potential indicators of CVD.

methodsIn this cross-sectional study, a total of 5,928 participants without cardiovascular disease (CVD), aged between 35 and 65 years, were included. Dietary egg consumption was evaluated using a validated food frequency questionnaire. The Minnesota coding system was employed to identify minor and major ischemic abnormalities on ECG. Odds ratios (ORs) for major and minor ischemic patterns across different egg consumption categories were calculated using multivariable logistic regression.

resultsUsing several statistical models, this study showed that higher egg consumption was associated with lower odds of isolated major ECG abnormalities in men, but not in women. In the fully adjusted model, consuming more than four eggs per week, compared to the lowest category (<1/week), was correlated with a 40% decrease in the odds of major ischemic changes on ECG in men (OR: 0.60, 95% CI: 0.39-0.93). Regarding minor ischemic abnormalities, there was no significant association with egg consumption in either women or men.

conclusionOur findings suggest a gender-specific effect of egg consumption on the presence of major ischemic changes on ECG. Further research is warranted to explore the underlying mechanisms and to inform tailored dietary guidelines for different populations.

Indexed as

Cardiovascular DiseaseEggElectrocardiographyIschemiaQ Wave

Identifiers

PMID40625821
PMCPMC12229173

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.