ReviewARYA atherosclerosis2025
Heart failure is the most negative consequence of CABG surgery (importance of exercise rehabilitation approach).
Review in ARYA atherosclerosis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundStatistics indicate that approximately 25,000 open-heart surgeries are performed annually in Iran, with coronary artery bypass grafting (CABG) surgeries accounting for 50-60% of these procedures. Although CABG offers numerous benefits to patients with coronary artery disease (CAD), some cases have reported negative consequences, such as heart failure (HF).
methodsThis study explored several influential blood indices related to HF following CABG surgery using manuscripts extracted from PubMed, Scopus, and Google Scholar. The analysis focused on indicators that can exacerbate HF, including fibrotic factors such as catecholamines and the renin-angiotensin-aldosterone system (RAAS).Conversely, it also investigated anti-fibrotic factors, including adrenomedullin (ADM), the natriuretic peptide system (NPS), NP-converting enzymes, and NP receptors. Additionally, the study evaluated the impact of various exercise training programs on these variables.
resultsSome fibrotic factors, such as catecholamines and the RAAS, contrast with anti-fibrosis factors, including NPs, their producing enzymes, receptors, production and excretion processes, ADM, and others. Research suggests these elements can be positively influenced by exercise rehabilitation.This study highlights the beneficial effects of exercise rehabilitation, specifically in reducing fibrotic factors and enhancing anti-fibrosis factors.
conclusionAll types of exercise training-including endurance, resistance, and combined training, in both continuous and interval modes with moderate and high intensity-can delay fibrotic pathways after surgery and prevent subsequent adverse structural (pathologic hypertrophy) and functional changes in the heart, such as HF.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.