Evidence map›Paper›PMID 40625742›Full record

ArticleFrontiers in immunology2025

PLGA nanoparticles as an efficient carrier in

Pan Zhou, YanLi Yu, WeiYu Qi, XiaoJuan Wang, YouLi Yu, JianDong Wang, Li Zhang, ZhengQing Yu, TingLi Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Advances and Translational Challenges inVeterinary sciences · 2026
    Review
  2. Veterinary sciences · 2026
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Pan ZhouSchool of Animal Science and Technology, Ningxia University, Yinchuan, China.
YanLi YuSchool of Economics and Management, Ningxia University, Yinchuan, China.
WeiYu QiSchool of Animal Science and Technology, Ningxia University, Yinchuan, China.
XiaoJuan WangSchool of Animal Science and Technology, Ningxia University, Yinchuan, China.
YouLi YuInstitute of Animal Science, Ningxia Academy of Agricultural and Forestry Science, Yinchuan, China.
JianDong WangInstitute of Animal Science, Ningxia Academy of Agricultural and Forestry Science, Yinchuan, China.
Li ZhangSchool of Animal Science and Technology, Ningxia University, Yinchuan, China.
ZhengQing YuSchool of Animal Science and Technology, Ningxia University, Yinchuan, China.
TingLi LiuDepartment of Medical Laboratory, Fenyang College of Shanxi Medical University, Fenyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Methods: In this study, we constructed a subunit vaccine using Results: The results demonstrated that TgGAP45-PLGA nanospheres induced a mixed Th1/Th2 immune response against Discussion: These findings indicate that TgGAP45 delivered via PLGA nanospheres is a promising candidate for preventing acute toxoplasmosis. Further studies and applications are warranted to explore its full therapeutic potential.

Indexed as

Antigens, ProtozoanNanoparticlesPolylactic Acid-Polyglycolic Acid CopolymerProtozoan ProteinsProtozoan VaccinesToxoplasmaToxoplasmosisToxoplasmosis, AnimalAnimalsAntibodies, ProtozoanCytokinesDendritic CellsDrug CarriersFemaleMiceMice, Inbred BALB CAntibodies, ProtozoanAntigens, ProtozoanCytokinesDrug CarriersPolylactic Acid-Polyglycolic Acid CopolymerProtozoan ProteinsProtozoan VaccinesVaccines, Subunitglidesome-associated protein 45immunoprotectionmicePLGA nanoparticlesToxoplasma gondii

Identifiers

PMID40625742
PMCPMC12229859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.