Evidence map›Paper›PMID 40625642›Full record

ArticlebioRxiv : the preprint server for biology2025

Crossover designation recruits condensin to reorganize the meiotic chromosome axis.

Victor A Leon, Tovah E Markowitz, Soogil Hong, Adhithi R Raghavan, Jonna Heldrich, Keun Kim, Andreas Hochwagen

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Victor A LeonDepartment of Biology, New York University; New York, NY 10012; USA.
Tovah E MarkowitzDepartment of Biology, New York University; New York, NY 10012; USA.
Soogil HongDepartment of Life Science, Chung-Ang University; Seoul, 06974; South Korea.
Adhithi R RaghavanDepartment of Biology, New York University; New York, NY 10012; USA.
Jonna HeldrichDepartment of Biology, New York University; New York, NY 10012; USA.
Keun KimDepartment of Life Science, Chung-Ang University; Seoul, 06974; South Korea.
Andreas HochwagenDepartment of Biology, New York University; New York, NY 10012; USA.ORCID 0000-0002-6184-443X

Funding

Mechanisms of programmed chromosome breakageR35GM148223 · NIGMS · NEW YORK UNIVERSITY · PI Andreas Hochwagen · 2023 to 2026
$2.3M
NIGMS NIH HHS R35 GM148223
6 · The paper itself

Abstract

Crossover recombination supports meiotic chromosome inheritance and fertility by establishing chiasmata between homologous chromosomes prior to the first meiotic division. In addition to the physical exchange of DNA mediated by meiotic recombination, chiasma formation also involves restructuring of the underlying chromosome axis, possibly to help with chiasma maturation or to resolve chromosomal interlocks. Here, we identify condensin as an important regulator of axis remodeling in

Indexed as

Axial elementPch2Rec8Red1synapsisZMM factors

Identifiers

PMID40625642
PMCPMC12232923

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.