Evidence map›Paper›PMID 40625523›Full record

ReviewSmart molecules : open access2024

Recent progress in stimuli-responsive DNA-based logic gates: Design, working principles and biological applications.

Ling Sum Liu, Hoi Man Leung, Yuzhen Cai, Pik Kwan Lo

Abstract readReview
In one paragraph

Review in Smart molecules : open access, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Proteinoid Computing on Olivine Substrates.Langmuir : the ACS journal of surfaces and colloids · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ling Sum LiuDepartment of Chemistry and State Key Laboratory of Marine Pollution City University of Hong Kong Kowloon Tong Hong Kong SAR China.ORCID https://orcid.org/0000-0002-2291-5493
Hoi Man LeungDepartment of Chemistry and State Key Laboratory of Marine Pollution City University of Hong Kong Kowloon Tong Hong Kong SAR China.ORCID https://orcid.org/0000-0002-0161-8027
Yuzhen CaiDepartment of Chemistry and State Key Laboratory of Marine Pollution City University of Hong Kong Kowloon Tong Hong Kong SAR China.
Pik Kwan LoDepartment of Chemistry and State Key Laboratory of Marine Pollution City University of Hong Kong Kowloon Tong Hong Kong SAR China.ORCID https://orcid.org/0000-0001-5255-1718

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stimuli-responsive DNA-based logic gates have emerged as a promising field at the intersection of synthetic biology and nanotechnology. These gates exploit the unique properties of DNA molecules to perform programmable computational operations in response to specific stimuli. This review provides a comprehensive overview of recent advancements in the design, working principles, and applications of stimuli-responsive DNA-based logic gates. The progress made in developing various types of logic gates triggered by metal ions, pH, oligonucleotides, small molecules, proteins, and light is highlighted. The applications of these logic gates in imaging and biosensing, drug delivery, synthetic biology and molecular computing are discussed. This review underscores the significant contributions and future prospects of stimuli-responsive DNA-based logic gates in advancing the field of nanotechnology.

Indexed as

DNA logic gatesdrug deliveryimagingmolecular computationstimuli‐responsive

Identifiers

PMID40625523
PMCPMC12118300

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.