ArticleCureus2025
Unusual Presentation of West Nile Virus Meningitis With Cerebrospinal Fluid (CSF) Neutrophilia in a 68-Year-Old Male.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The first outbreak of neuroinvasive West Nile virus infection in Istanbul area within 2019.BMC infectious diseases · 2026Article
- CSF Leukocytes in Intracranial Infections: Diagnostic, Mechanistic, and Therapeutic Insights for Neurocritical Care.Cellular and molecular neurobiology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
West Nile virus (WNV), a mosquito-borne flavivirus, can cause neuroinvasive disease, including meningitis, encephalitis, and acute flaccid paralysis. WNV meningitis typically presents with lymphocytosis in the cerebrospinal fluid (CSF). We report a case of a 68-year-old male who presented with dizziness, syncope, and head trauma, accompanied by headache, neck pain, and fever (102.3 °F), but without confusion or photophobia. The initial workup was unremarkable, but the lumbar puncture revealed elevated cerebrospinal fluid (CSF) opening pressure, neutrophilic pleocytosis, and increased red blood cells, protein, and glucose levels. CSF serology was positive for WNV IgM, and other infectious etiologies were excluded. This case illustrates that WNV meningitis may present with atypical CSF neutrophilic predominance, emphasizing the need to consider WNV in the differential diagnosis of meningitis, especially during mosquito season or in endemic areas, even when CSF findings are non-classical. Early recognition and diagnostic testing are essential for appropriate management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.