Evidence map›Paper›PMID 40625484›Full record

ArticleCureus2025

Nitrous Oxide: No More a Laughing Matter.

Amit Badshah, Abir Aijaz, Abdul Bhat, Ayesha Babar

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amit BadshahAcute and General Internal Medicine, Weston General Hospital, University Hospitals Bristol and Weston, Weston-super-Mare, GBR.
Abir AijazAcute and General Internal Medicine, Weston General Hospital, University Hospitals Bristol and Weston, Weston-super-Mare, GBR.
Abdul BhatAcute and General Internal Medicine, Weston General Hospital, University Hospitals Bristol and Weston, Weston-super-Mare, GBR.
Ayesha BabarAcute Medicine, Weston General Hospital, University Hospitals Bristol and Weston, Weston-super-Mare, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nitrous oxide (N₂O) is an uncommon cause of subacute combined degeneration (SCD) of the spinal cord, typically observed in district general hospitals, with most affected patients being male. A genetic predisposition may contribute to the development of this myelopathy, particularly due to polymorphisms in the gene responsible for vitamin B12 processing. Our case is distinct in its presentation, involving prolonged exposure over two years, thoracic dorsal column involvement, and rapid, significant recovery within two months.

Indexed as

ataxiacanisterfolatehydroxocobalamininhalationnitrous oxidespinal cordspinal mrisubacute combined degeneration of the spinal cordvitamin b12

Identifiers

PMID40625484
PMCPMC12229834

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.