Evidence map›Paper›PMID 40625474›Full record

ArticleCureus2025

Thoracic Back Pain Leading to an Acromegaly Diagnosis: A Case Report.

Ammar Siddiqui, Melissa Chao, Michael Rahimi, Alla Spivak, Michael Weinberger

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ammar SiddiquiAnesthesiology, New York Medical College, Valhalla, USA.
Melissa ChaoAnesthesiology, Columbia University, New York, USA.
Michael RahimiAnesthesiology, New York Medical College, Valhalla, USA.
Alla SpivakAnesthesiology, New York Medical College, Valhalla, USA.
Michael WeinbergerAnesthesiology, Columbia University, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse idiopathic skeletal hyperostosis (DISH), a common cause of thoracic backache, may be caused by unregulated growth factor activity by increasing enthesis and bony growth. Excess growth factors can cause acromegaly. We describe the case of a patient presenting with chronic thoracic axial back pain for several decades and features of acromegaly on history and physical exam. Single photon emission computed tomography (SPECT) CT was obtained to identify the pain generator and detected increased metabolic activity in the anterior column suggestive of DISH. Subsequent laboratory testing revealed acromegaly. Follow-up imaging identified a growth hormone (GH)-secreting pituitary macroadenoma with local invasion. To the best of our knowledge, this is the first time the finding of DISH has hinted at the possibility of acromegaly, and may illustrate the need for added vigilance for acromegaly in patients with DISH.

Indexed as

acromegalyback paindiffuse idiopathic skeletal hyperostosis (dish)growth hormonemid back pain

Identifiers

PMID40625474
PMCPMC12234160

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.