Evidence map›Paper›PMID 40625454›Full record

ArticlePediatric discovery2024

Prognostic impact of MALs and potential immunotherapy targets in uveal melanoma.

Jing Yang, Zhou Fu, Qin Xiang

Abstract read
In one paragraph

Article in Pediatric discovery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jing YangOphthalmology Department Children's Hospital of Chongqing Medical University Chongqing China.
Zhou FuOphthalmology Department Children's Hospital of Chongqing Medical University Chongqing China.
Qin XiangOphthalmology Department Children's Hospital of Chongqing Medical University Chongqing China.ORCID https://orcid.org/0009-0005-6228-3450

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uveal melanoma (UM) is the most common primary ocular malignancy in adults, and the 5-year disease-related mortality rate is 30%. MAL proteolipid family (MALs), including T-cell differentiation protein (MAL), T-cell differentiation protein 2 (MAL2), and T-cell differentiation protein like (MALL), were involved in the progression and prognosis of many different cancers. However, the role of MALs in UM was not reported. UM samples were extracted from The Cancer Genome Atlas. R software (R3.6.3) was used to comprehensively analyze the roles of the MALs (significance threshold:

Indexed as

immunotherapy targetMAL proteolipid familyprognosis biomarkeruveal melanoma

Identifiers

PMID40625454
PMCPMC12118173

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.