ArticleFrontiers in medicine2025
Association between dietary vitamin B2 intake and constipation: a nationwide cross-sectional study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- A Review ofFoods (Basel, Switzerland) · 2026Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: A multitude of studies has suggested a possible link between the intake of dietary micronutrients and the incidence of constipation. Nevertheless, there exists a significant gap in research that specifically addresses the relationship between vitamin B2 and constipation. The present investigation seeks to explore the possible correlation between dietary intake of vitamin B2 and chronic constipation in adult participants surveyed in the National Health and Nutrition Examination Survey (NHANES). Methods: This research leveraged data from the NHANES conducted between 2005 and 2010. Dietary intake information was obtained from participants through 24 h dietary recall interviews. Various statistical approaches, including weighted logistic regression, interaction tests, subgroup analyses, and restricted cubic spline, were utilized to examine the relationship between dietary vitamin B2 consumption and the occurrence of constipation. Results: A comprehensive multiple logistic regression analysis that accounted for various confounding factors indicated that individuals with the highest quartile of vitamin B2 intake exhibited a significantly reduced risk of experiencing constipation (OR = 0.63; 95% CI, 0.47-0.84) in comparison to those situated in the lowest quartile. Furthermore, a continuous assessment of vitamin B2 intake demonstrated an inverse relationship with constipation (OR = 0.89, 95% CI, 0.81-0.98). The implementation of restricted cubic splines suggested a linear association between vitamin B2 consumption and constipation ( Conclusion: This investigation highlights an inverse relationship between the dietary intake of vitamin B2 and constipation within the adult population of the United States.
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