Evidence map›Paper›PMID 40625220›Full record

Trial reportClinical oral implants research2025

Radiographic Peri-Implant Bone Changes in Osteoporotic Women Treated With a Ti-Zr, Bone Level Tapered Implant With a Hydrophilic Surface: A 12-Month Prospective Case-Series.

Calciolari Elena, Mardas Nikos, Palaska Iro, Tagliaferri Sara, Donos Nikolaos

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Clinical oral implants research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02884401 (Radiographic Peri-implant Alveolar Bone Changes in Post-menopausal Osteoporotic Women), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02884401 nacompletednot on this map

Radiographic Peri-implant Alveolar Bone Changes in Post-menopausal Osteoporotic Women

TypeinterventionalSponsorQueen Mary University of LondonRan2016 to 2022Enrolled27ConditionsOsteoporosis, PostmenopausalArmsDental implant placement (Straumann® Bone Level Tapered, BLT, Roxolid® SLActive®)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Calciolari ElenaCentre for Oral Clinical Research, Institute of Dentistry, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID 0000-0001-8781-1997
Mardas NikosCentre for Oral Clinical Research, Institute of Dentistry, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID 0000-0002-6841-458X
Palaska IroCentre for Oral Clinical Research, Institute of Dentistry, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.
Tagliaferri SaraDepartment of Medicine and Surgery, University of Parma, Parma, Italy.
Donos NikolaosCentre for Oral Clinical Research, Institute of Dentistry, Faculty of Medicine and Dentistry, Queen Mary University of London, London, UK.ORCID 0000-0002-4117-9073

Funding

Institut Straumann CH-270.3.013.818-1Institut Straumann Registernumber
6 · The paper itself

Abstract

objectivesThis study assessed 12-month post-loading 3D peri-implant radiographic bone changes in osteoporotic women receiving a single titanium-zirconium bone-level tapered dental implant with a hydrophilic surface. MATERIALS AND

methodsThis was a prospective case series involving 18 post-menopausal osteoporotic women in need of a single dental implant. A standardized CBCT scan was performed after implant placement and at 12 months post-loading to assess peri-implant bone changes. The Implant Stability Quotient (ISQ) was recorded after implant placement, at implant impression, loading, and 12 months post-loading. Peri-implant clinical parameters were recorded at 6 and 12 months post-loading and during the last visit implant survival and success were also evaluated.

resultsSeventeen patients completed all study visits, and implant placement was uneventful for all participants. A statistically significant difference (reduction) from implant placement to 12 months post-loading was observed in terms of radiographic buccal bone width and palatal/lingual width (ΔBw-0: 0.53 mm, p < 0.001 and ΔPw-0: 0.47 mm, p = 0.006), as well as in terms of vertical distance between the implant shoulder and the first bone to implant contact on the buccal and palatal/lingual aspect (ΔBICb: -0.26 mm, p = 0.005 and ΔBICp: -0.46 mm, p = 0.018). ISQ increased during osseointegration, and a high implant survival (100%) and success rate (from 81.3% to 100% based on 3 different sets of criteria) were recorded at 12 months post-loading.

conclusionIn this case series, osteoporotic patients treated with single titanium-zirconium implants showed high survival rates, predictable 12-month implant outcomes, and physiologic peri-implant bone remodelling.

trial registrationNCT02884401.

Indexed as

Dental Implantation, EndosseousDental Implants, Single-ToothDental Prosthesis DesignOsteoporosis, PostmenopausalAgedCone-Beam Computed TomographyDental ImplantsFemaleHumansHydrophobic and Hydrophilic InteractionsMiddle AgedProspective StudiesSurface PropertiesTitaniumTreatment OutcomeZirconiumDental ImplantsTitaniumZirconiumbone regenerationdental implantationosseointegrationosteoporosispost‐menopausal

Identifiers

PMID40625220
PMCPMC12491925

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.