Evidence map›Paper›PMID 40625219›Full record

ArticleJournal of evidence-based integrative medicine

Ganoderma Spore Lipids Inhibit Perineural Invasion in Pancreatic Cancer by Downregulating NGF-TrkA Pathway.

Haohui Lin, Manhon Chung, Yi Yang, Li Zhang, Xiaohua Pan, Sa Cai, Yu Pan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of evidence-based integrative medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Haohui LinLaboratory of Regenerative Medicine, The 2nd Affiliated Hospital of Shenzhen University, Medical School, Shenzhen University, Shenzhen, China.
Manhon ChungDepartment of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yi YangLaboratory of Regenerative Medicine, The 2nd Affiliated Hospital of Shenzhen University, Medical School, Shenzhen University, Shenzhen, China.
Li ZhangLaboratory of Regenerative Medicine, The 2nd Affiliated Hospital of Shenzhen University, Medical School, Shenzhen University, Shenzhen, China.
Xiaohua PanLaboratory of Regenerative Medicine, The 2nd Affiliated Hospital of Shenzhen University, Medical School, Shenzhen University, Shenzhen, China.
Sa CaiLaboratory of Regenerative Medicine, The 2nd Affiliated Hospital of Shenzhen University, Medical School, Shenzhen University, Shenzhen, China.ORCID 0000-0002-1370-0028
Yu PanLaboratory of Regenerative Medicine, The 2nd Affiliated Hospital of Shenzhen University, Medical School, Shenzhen University, Shenzhen, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perineural invasion (PNI) is an important factor leading to the recurrence of pancreatic cancer (PanCa). The NGF-TrkA pathway is related to PNI progression.

Indexed as

GanodermaLipidsNerve Growth FactorPancreatic NeoplasmsReceptor, trkASpores, FungalAnimalsCell Line, TumorCell MovementDown-RegulationHumansMaleMiceMice, Inbred BALB CNeoplasm InvasivenessSignal TransductionLipidsNerve Growth FactorReceptor, trkAGanoderma spore lipidNGF–TrkA pathwaypancreatic cancerperineural invasion

Identifiers

PMID40625219
PMCPMC12246538

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.