Evidence map›Paper›PMID 40625184›Full record

ArticleJournal of diabetes investigation2025

The prevalence of hepatitis B infection and anti-HCV antibody in patients with diabetes mellitus.

Malihe Naderi, Seyed Masoud Hosseini, Vahideh Hamidi, Abdolvahab Moradi

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Article in Journal of diabetes investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Malihe NaderiHiroshima Institute of Life Sciences, Hiroshima, Japan.ORCID https://orcid.org/0000-0002-3723-4340
Seyed Masoud HosseiniDepartment of Microbiology and Microbial Biotechnology, Faculty of Life Sciences and Biotechnology, Shahid Beheshti University, Tehran, Iran.ORCID https://orcid.org/0000-0002-8906-5833
Vahideh HamidiDepartment of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.
Abdolvahab MoradiDepartment of Microbiology, Faculty of Medicine, Golestan University of Medical Sciences, Gorgan, Iran.ORCID https://orcid.org/0000-0003-2877-4190

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe liver's role in glucose metabolism and hormone regulation links liver infections to diabetes mellitus. Understanding this interaction is crucial for managing diabetes in affected patients.

objectiveGolestan Province has the highest incidence of hepatitis B virus (HBV) infection in the country. The current research aimed to assess the prevalence of HBV infection and anti-HCV antibodies among diabetic patients in the region, providing insights to improve disease management and prevention.

methodsData from 31,803 diabetic patients, collected (2019-2023) from the NAB system at Golestan University of Medical Sciences, were used to evaluate the co-occurrence of HBV infection and anti-HCV antibodies in them. Also, this study analyzed the co-occurrence of diabetes in three/two-generation CHB (Chronic Hepatitis B) patients, and recovered patients, demographic factors, liver enzyme, and viral DNA levels. Binary logistic regression was applied to identify factors associated with diabetes.

resultsHBsAg and anti-HCV antibody positivity were found in 2.52% and 0.53% of diabetic individuals, respectively. Diabetic patients with HBV infection (P-value = 0.003) or anti-HCV positivity (P-value = 0.008) had significantly lower BMIs. HBV prevalence was higher among married individuals (78.4%, P-value = 0.01) and rural residents (61.7%, P-value = 0.3). Diabetic patients with two or three generations of HBV/diabetes had higher liver enzyme levels and HBV viral loads compared to those without diabetes (P-value < 0.05).

conclusionsIn individuals with diabetes, compared to those without the disease, there was a correlation between HBV infections and altered liver function indicators, as well as HBV viral load. Additionally, familial susceptibility to HBV infection or anti-HCV antibody positivity was significant.

Indexed as

Diabetes MellitusHepatitis BHepatitis CHepatitis C AntibodiesAdultAgedFemaleHepacivirusHepatitis B virusHumansIranMaleMiddle AgedPrevalencePrognosisHepatitis C AntibodiesAnti‐HCVHepatitis B virusMetabolic diseases

Identifiers

PMID40625184
PMCPMC12400377

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