Evidence map›Paper›PMID 40625163›Full record

SynthesisSeminars in dialysis

Prevalence and Risk Factors of Sarcopenia in People Receiving Dialysis: A Systematic Review and Meta-Analysis.

Joanna Stockings, Susan Heaney, Ginger Chu, Peter Choi, Ritin Fernandez

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Seminars in dialysis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joanna StockingsJohn Hunter Hospital, New Lambton Height, Australia.
Susan HeaneyDepartment of Rural Health, University of Newcastle, Port Macquarie, New South Wales, Australia.ORCID 0000-0001-8206-4080
Ginger ChuSchool of Nursing and Midwifery, University of Newcastle, Callaghan, New South Wales, Australia.ORCID 0000-0001-7096-0144
Peter ChoiJohn Hunter Hospital, New Lambton Height, Australia.
Ritin FernandezSchool of Nursing and Midwifery, University of Newcastle, Callaghan, New South Wales, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople receiving dialysis treatment are at higher risk of sarcopenia. This review aimed to determine the global prevalence of sarcopenia in people on peritoneal dialysis and hemodialysis. We investigated whether the prevalence of sarcopenia differs based on assessment criteria, timing of assessment, and measurement tools used and explored the risk factors for sarcopenia in people on dialysis.

methodsThis review followed JBI and PRISMA guidelines and included studies assessing sarcopenia in adults aged 18 and older with chronic kidney disease undergoing dialysis. Five databases were searched from inception to November 2022. The JBI SUMARI software was used to perform the meta-analysis. Publication bias and risk factor analysis were performed using STATA (Version 18).

resultsA meta-analysis of 62 studies (15,382 participants) found the global prevalence of sarcopenia to be 30.1% (95% CI: 25.6%-39.9%) for hemodialysis and 20.5% (95% CI: 15.1%-26.4%) for peritoneal dialysis. Sarcopenia prevalence ranged between 23.1% and 30.3% in HD and between 6.1% and 26.9% in PD, based on the assessment criteria. Post-dialysis sarcopenia prevalence was higher (33%) than pre-dialysis (24.2%) in hemodialysis patients. Measuring muscle mass after dialysis using dual-energy X-ray assessment yielded a lower prevalence of sarcopenia (22.5%) than bioimpedance analysis or spectroscopy (33%). Risk factors in the HD population included age, sex, diabetes, inflammation markers, nutritional indices, and dialysis vintage, although heterogeneity between studies was high.

conclusionThis study showed a high prevalence of sarcopenia among the dialysis population and identified many risk factors, emphasizing the need for early identification and intervention and standardized assessments.

Indexed as

Kidney Failure, ChronicPeritoneal DialysisRenal DialysisRenal Insufficiency, ChronicSarcopeniaAdultAgedFemaleHumansMaleMiddle AgedPrevalenceRisk Factorshemodialysismeta‐analysisperitoneal dialysissarcopenia

Identifiers

PMID40625163
PMCPMC12378093

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.