Evidence map›Paper›PMID 40625152›Full record

ArticleChemistry, an Asian journal2025

Deep Eutectic Solvents as More Sustainable Dispersion Media for Beeswax Coatings from Cultural Heritage: Experimental Insights and Theoretical Modeling.

Andrea Macchia, Raffaella Mancuso, Romina Strangis, Irene Angela Colasanti, Mariangela Novello, Mauro Francesco La Russa, Bartolo Gabriele, Roberto Beneduci

Abstract read
In one paragraph

Article in Chemistry, an Asian journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Andrea MacchiaYOCOCU (YOuth in COnservation of CUltural Heritage), Via T. Tasso 108, Rome, 00185, Italy.
Raffaella MancusoLaboratory of Industrial and Synthetic Organic Chemistry (LISOC), Department of Chemistry and Chemical Technologies, University of Calabria, Via Pietro Bucci 12/C, Arcavacata di Rende, CS, 87036, Italy.ORCID https://orcid.org/0000-0001-7514-6096
Romina StrangisLaboratory of Industrial and Synthetic Organic Chemistry (LISOC), Department of Chemistry and Chemical Technologies, University of Calabria, Via Pietro Bucci 12/C, Arcavacata di Rende, CS, 87036, Italy.
Irene Angela ColasantiYOCOCU (YOuth in COnservation of CUltural Heritage), Via T. Tasso 108, Rome, 00185, Italy.
Mariangela NovelloLaboratory of Industrial and Synthetic Organic Chemistry (LISOC), Department of Chemistry and Chemical Technologies, University of Calabria, Via Pietro Bucci 12/C, Arcavacata di Rende, CS, 87036, Italy.
Mauro Francesco La RussaDepartment of Biology, Ecology and Earth Science (DiBEST), University of Calabria, Arcavacata di Rende, CS, 87036, Italy.
Bartolo GabrieleLaboratory of Industrial and Synthetic Organic Chemistry (LISOC), Department of Chemistry and Chemical Technologies, University of Calabria, Via Pietro Bucci 12/C, Arcavacata di Rende, CS, 87036, Italy.
Roberto BeneduciDepartment of Physics, University of Calabria, and INFN gruppo coll. Cosenza, via P. Bucci 31/C, Arcavacata di Rende, CS, 87036, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deep eutectic solvents (DESs) are gaining attention as sustainable alternatives to traditional organic solvents, particularly for applications involving nonpolar substances. In this study, the dispersion behavior of beeswax in a selection of hydrophobic natural deep eutectic solvents (hNADESs) was investigated using both theoretical and experimental approaches. The compatibility between each DES and beeswax was first assessed through Hansen solubility parameters and RED (relative energy difference) values. Based on these results, a subset of DESs was selected for kinetic testing. Turbidimetric and gravimetric measurements were carried out over time to monitor the dispersion process. The experimental data were then fitted using a simplified Hill-type kinetic model, which successfully described the nonlinear, saturation-limited behavior observed in the systems. DES 8, composed of dodecanoic and decanoic acids, showed the highest dispersion capacity, while DES 6 (tymol and L-(-)-menthol) exhibited moderate performance. DES 12, containing choline chloride and diglycolic acid, showed negligible activity. The findings highlight the relevance of combining solubility theory with kinetic modeling to evaluate hNADES performance. The proposed approach offers a useful tool for predicting and optimizing dispersion processes in structured, low-toxicity solvents.

Indexed as

BeeswaxCultural heritageGreen solventsHydrophobic natural deep eutectic solventsKinetic modelingRegression models

Identifiers

PMID40625152
PMCPMC12450040

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.