ArticleBJPsych open2025
Bidirectional relationships between cognition and depressive symptoms and effects of sociodemographic and lifestyle factors: random-intercept, cross-lagged panel model.
Article in BJPsych open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Bidirectional associations between loneliness and physical multimorbidity and the mediating role of social inactivity.Nature communications · 2026Article
- No Cognitive Scarring Over 20 Years in Recurrent Depression: Bidirectionality of Cognitive Functioning and Depression.Clinical psychology in Europe · 2026Article
- Independent, joint, and temporal associations of social, intellectual, and physical leisure activities with cognitive decline in older Chinese adults: a longitudinal analysis from CHARLS.BMC geriatrics · 2026Article
- The bidirectional relationship between depression and cognitive function in older adults: evidence from a psychosocial intervention on late-life depression.Innovation in aging · 2026Article
- Reciprocal association between dietary diversity and subjective well-being in Chinese older adults: a three-wave longitudinal study.Archives of public health = Archives belges de sante publique · 2025Article
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4 authors.
Funding
Abstract
backgroundExisting panel studies on the relationships between cognition and depressive symptoms did not systematically separate between- and within-person components, with measurement time lags that are too long for precise assessment of dynamic within-person relationships.
aimsTo investigate the bidirectional relationships between cognition and depressive symptoms and examine the effects of sociodemographic characteristics and lifestyle factors via random-intercept, cross-lagged panel modelling (RI-CLPM) in middle-aged and older adults.
methodThe sample comprised 24 425 community-based residents aged 45 years or above, recruited via five waves of the China Health and Retirement Longitudinal Study (2011-2020). Cognition was evaluated using the Telephone Interview of Cognition Status, and depressive symptoms were assessed by the ten-item Center for Epidemiologic Studies Depression Scale. RI-CLPM included sociodemographic and lifestyle factors as time-invariant and -varying covariates. Subgroup analysis was conducted across gender, age groups and urban/rural regions.
resultsRI-CLPM showed a superior fit to cross-lagged panel models. Male, higher education, married, urban region, non-smoking, currently working and participation in social activities were linked with better cognition and fewer depressive symptoms. Overall, cognition and depressive symptoms showed significant and negative bidirectional cross-lagged effects over time. Despite similar cross-lagged effects across gender, subgroup analysis across urbanicity found that cross-lagged effects were not significant in urban regions.
conclusionsThe present study provided nuanced results on negative bidirectional relationships between cognition and depressive symptoms in Chinese middle-aged and older adults. Our results highlight the health disparities in cognitive and emotional health across urbanicity and age groups.
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