Evidence map›Paper›PMID 40625015›Full record

ArticleNeurospine2025

Endoscopic Transnasal Approach to Atlantoaxial Decompression and C1-2 Fixation in Basilar Invagination of Adults: A Feasibility Study.

Jiahai Ding, Shao Xie, Yuliang Chen, Runchuan Zhou, Syed Matiullah Azizi, Xiaoya Huang, Yang Xiong, Yuancheng Yao, Yushun Zhang, Yong Liu and 1 more

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Article in Neurospine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Jiahai DingDepartment of Neurosurgery, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Shao XieDepartment of Neurosurgery, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Yuliang ChenDepartment of Neurosurgery, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Runchuan ZhouDepartment of Neurosurgery, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Syed Matiullah AziziDepartment of Neurosurgery, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Xiaoya HuangThe First Clinical College of Xuzhou Medical University, Xuzhou, China.
Yang XiongDepartment of Neurosurgery, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Yuancheng YaoDepartment of Neurosurgery, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Yushun ZhangDepartment of Neurosurgery, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Yong LiuDepartment of Neurosurgery, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.
Lei WangDepartment of Neurosurgery, the Affiliated Hospital of Xuzhou Medical University, Xuzhou, China.

Funding

Jiangsu Provincial Key Medical Discipline ZDXK202228Xuzhou Science and Technology Plan Project KC20139
6 · The paper itself

Abstract

objectiveTo explore a surgical technique for completing ventral bone decompression and C1-2 plate-screw fixation in the craniocervical junction (CVJ) through nasal approach by stage I at the imaging and physical anatomy levels, and to evaluate its feasibility.

methodsRadiographic parameters of 80 patients with basilar invagination (BI) and 56 with normal CVJ anatomy were retrospectively analyzed. Three-dimensional (3D) reconstructions were performed in 31 patients with BI. Key anatomical landmarks, screw entry points, and fixation trajectories were evaluated. Customized plate-screw constructs were designed. Finally, surgical feasibility was tested on a 3D-printed anatomical model and a cadaveric.

resultsIn 80 BI patients, the average distances between 4 screw insertion points were 16.04 mm, 21.10 mm, 6.83 mm, and 7.10 mm. C2 lateral mass oblique lengths were 16.81 mm (right) and 17.12 mm (left); C1 lengths were 18.71 mm (right) and 19.07 mm (left), with significant differences between C1 and C2 (p<0.001). A 28.5×14.1-mm titanium plate with 16 mm screws was successfully implanted via the nasal route in the polyether ether ketone 3D-printed BI model and the cadaveric. Radiology indicated that the screws were all in the lateral mass and the plates fit tightly.

conclusionIn BI, transnasal odontoidectomy and plate-screw fixation of C1-2 are feasible theoretically. This may enable a new alternative approach for nasal minimally invasive decompression and immobilization, following the completion of biomechanics and clinical trials.

Indexed as

Basilar invaginationC1–2 fixationCraniovertebral junctionOdontoidectomyTransnasal

Identifiers

PMID40625015
PMCPMC12242732

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