Evidence map›Paper›PMID 40624898›Full record

SynthesisCerebral cortex (New York, N.Y. : 1991)2025

Neural networks underlying magnitude perception: a specific meta-analysis of fMRI studies.

Hazal Şimşek-Ünver, Burcu Sırmatel-Bakrıyanık, Beyza Doğanay, Fuat Balcı, Metehan Çiçek

Abstract readMeta-Analysis
In one paragraph

Synthesis in Cerebral cortex (New York, N.Y. : 1991), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hazal Şimşek-ÜnverDepartment of Physiology, School of Medicine, Ankara University, Adnan Saygun St., Hacettepe, 06230, Altındağ, Ankara, Türkiye.
Burcu Sırmatel-BakrıyanıkNeuroscience and Neurotechnology Center of Excellence (NÖROM), Milas St., Emniyet, 06560, Yenimahalle Ankara, Türkiye.
Beyza DoğanayDepartment of Biostatistics, School of Medicine, Ankara University, Adnan Saygun St., Hacettepe, 06230, Altındağ, Ankara, Türkiye.
Fuat BalcıDepartment of Psychology, Koç University, Sarıyer Rumeli Feneri St., Rumelifeneri, 34450, Sarıyer, Istanbul, Türkiye.
Metehan ÇiçekNeuroscience and Neurotechnology Center of Excellence (NÖROM), Milas St., Emniyet, 06560, Yenimahalle Ankara, Türkiye.

Funding

Scientific and Technological Research Council of Turkey 112K293
6 · The paper itself

Abstract

Daily life requires simultaneously processing spatial, temporal, and numerical inputs to form a valid mental representation of the environment. The interrelation between these perceptions has been a subject of theoretical debate. For instance, a theory of magnitude (ATOM) asserts that magnitude perceptions are processed in overlapping brain areas, which has been tested in behavioral and neuroimaging studies. We aimed to combine functional magnetic resonance imaging (fMRI) results using a coordinate-based meta-analysis to test this primary assumption of ATOM regarding overlapping brain areas. We conducted separate literature searches for space, time, and number perception following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The analysis was based on 19 articles regarding space, 38 regarding time, and 31 regarding number perception. Coordinates were analyzed using the "Activation Likelihood Estimation" method, which focused on conjunction analysis. Double conjunction analyses revealed activations mainly in the fronto-parietal areas and insular cortex. The triple conjunction analysis revealed activations in the right hemisphere, specifically in the inferior parietal and inferior frontal areas (previously linked to magnitude perception) and the anterior insular cortex (implicated in interoception and salience). In support of the ATOM theory, these findings suggest that overlapping neural networks may underlie space, time, and number perceptions.

Indexed as

BrainNerve NetSpace PerceptionBrain MappingHumansMagnetic Resonance Imagingactivation likelihood estimation (ALE)number perceptionspace perceptiontime perception

Identifiers

PMID40624898
PMCPMC12235004

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.