Evidence map›Paper›PMID 40624876›Full record

ArticleHand (New York, N.Y.)2026

Bilateral Kienböck Disease: Associations With Demographic, Systemic, and Radiologic Findings.

Andrew F Emanuels, Jess Rames, Mehmet Furkan Tunaboylu, Steven L Moran

Abstract read
In one paragraph

Article in Hand (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrew F EmanuelsMayo Clinic, Rochester, MN, USA.
Jess RamesMayo Clinic, Rochester, MN, USA.
Mehmet Furkan TunaboyluMayo Clinic, Rochester, MN, USA.
Steven L MoranMayo Clinic, Rochester, MN, USA.ORCID 0009-0000-6870-3368

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKienböck disease most frequently affects 1 wrist and rarely occurs bilaterally. The purpose of this study is to describe the natural history and identify risk factors for development of bilateral Kienböck disease.

methodsAfter institutional review board approval, 350 patients with surgically managed Kienböck disease from 1976 to 2023 were identified. A retrospective review of the electronic medical record was used to collect demographic, clinical, and radiographic information. Two-tailed student

resultsTen of 350 patients (2.9%) had bilateral disease. The mean age was 45 (range: 14-62) years, and 6 out of 10 patients were female. The mean follow-up time was 47 (range: 9-274) months. Three of the 10 patients were laborers. Antecedent trauma (n = 2), prior corticosteroid injection (n = 1), and concomitant autoimmune disease (n = 1) were rare events. There was no difference in Lichtman Stage comparing the dominant and nondominant hands, and 72.2% of wrists were ulnar negative. This was higher but not significantly different than the unilateral affected comparison cohort (60%). Sufficient power was demonstrated (0.99). Eighteen of 20 wrists were treated operatively. Two cases required operative revision due to progression of disease.

conclusionsThe cause of bilateral versus unilateral Kienböck disease remains unclear. Bilateral disease was not associated with a higher incidence of autoimmune disease, systemic corticosteroid use, or exposure to heavy manual labor. However, thrombosis leading to avascular necrosis of the lunate may be influenced by hypercoagulable and inflammatory diseases. Surgeons should maintain a high index of suspicion for bilateral disease in patients with these comorbidities. Routine screening of the contralateral wrist is unjustified if the patient is asymptomatic.

Indexed as

OsteonecrosisWrist JointAdolescentAdultFemaleHumansLunate BoneMaleMiddle AgedRadiographyRetrospective StudiesRisk FactorsYoung Adultavascular necrosisbilateral Kienböck diseaseKienböck diseasepatient reported outcomesulnar variance

Identifiers

PMID40624876
PMCPMC12237944

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.