Evidence map›Paper›PMID 40624830›Full record

ArticleDrug and alcohol review2025

Gender and Overdose Risk Factors Among Clients Entering Residential Treatment for Opioid Use.

Chloe J Haynes, Alison K Beck, Peter J Kelly, Mei Lin Lee, Robert Stirling, Suzie Hudson, Laura Robinson, Michele Campbell, Carolyn Stubley, Briony Larance

Abstract read
In one paragraph

Article in Drug and alcohol review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chloe J HaynesSchool of Psychology, University of Wollongong, Wollongong, Australia.ORCID 0000-0003-2779-5950
Alison K BeckSchool of Psychology, University of Wollongong, Wollongong, Australia.ORCID 0000-0002-9031-2117
Peter J KellySchool of Psychology, University of Wollongong, Wollongong, Australia.ORCID 0000-0003-0500-1865
Mei Lin LeeNetwork of Alcohol and Other Drug Agencies, Sydney, Australia.
Robert StirlingNetwork of Alcohol and Other Drug Agencies, Sydney, Australia.ORCID 0000-0002-0596-8286
Suzie HudsonCentre for Alcohol and Other Drugs, NSW Ministry of Health, Sydney, Australia.
Laura RobinsonSchool of Psychology, University of Wollongong, Wollongong, Australia.ORCID 0000-0002-3409-475X
Michele CampbellNetwork of Alcohol and Other Drug Agencies, Sydney, Australia.
Carolyn StubleyNetwork of Alcohol and Other Drug Agencies, Sydney, Australia.
Briony LaranceSchool of Psychology, University of Wollongong, Wollongong, Australia.ORCID 0000-0003-3800-7673

Funding

Australian Government Research Training ProgramNational Health and Medical Research Council Meaningful Outcomes in Substance Use Treatment Centre of Research Excellence
6 · The paper itself

Abstract

introductionThe period post-residential treatment for opioid use is associated with heightened risk of overdose. The current study aims to: (i) describe characteristics of men and women attending residential treatment for primary opioid use; (ii) identify classes of clients based on primary opioid and other substance/s of concern and (iii) identify relationships between substance use profile and sociodemographic risk factors for opioid overdose, including differences by gender.

methodsData from 2994 clients (29.6% women) attending residential treatment for opioid use in the non-government sector in New South Wales, Australia, were included in the analysis. Descriptive and chi-square statistics analysed demographic, clinical, substance use and service use characteristics of participants. Participants were grouped using latent class analysis based on their primary opioid of concern and other substance/s of concern. Multinomial logistic regression examined the relationship between latent classes and sociodemographic risk factors for overdose, including interactions with gender.

resultsMen and women presented to residential treatment with different demographic, clinical, substance use and service use characteristics. A five-class model of polysubstance use was identified: heroin + lower polysubstance use (52.3%), heroin + polysubstance use (22.2%), pharmaceutical + lower polysubstance use (10.1%), pharmaceutical + polysubstance use (6.7%) and OAT + polysubstance use (8.7%). There were some associations between sociodemographic risk factors and class membership, though limited interactions between sociodemographic risk and gender. DISCUSSION AND

conclusionsEffective overdose prevention and harm reduction strategies during and post-residential treatment need to consider individuals' complex and unique accumulation of risk.

Indexed as

Analgesics, OpioidDrug OverdoseOpioid-Related DisordersResidential TreatmentAdultFemaleHumansMaleMiddle AgedNew South WalesRisk FactorsSex FactorsYoung AdultAnalgesics, Opioidlatent class analysisopioid useoverdosepolysubstance useresidential treatment

Identifiers

PMID40624830
PMCPMC12405814

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.