Evidence map›Paper›PMID 40624827›Full record

ArticleMolecular microbiology2025

Role of the Multicopper Oxidase CueO in Copper Homeostasis Under Anaerobic Conditions in Enterobacteria.

Jérôme Becam, Maxence Dessertine, Alexandra Vergnes, Laurent Aussel, Benjamin Ezraty

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. A Putative Multicopper Oxidase Encoded byInternational journal of molecular sciences · 2026
    Article
  2. Review
  3. CueO Possesses Copper Detoxification Activity Linking Bacterial Virulence and Drug Resistance in Brucella.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jérôme BecamLaboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, CNRS, Aix-Marseille University, Marseille, France.ORCID 0009-0009-8556-6671
Maxence DessertineLaboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, CNRS, Aix-Marseille University, Marseille, France.
Alexandra VergnesLaboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, CNRS, Aix-Marseille University, Marseille, France.ORCID 0000-0001-6745-6633
Laurent AusselLaboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, CNRS, Aix-Marseille University, Marseille, France.ORCID 0000-0001-5239-4556
Benjamin EzratyLaboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, CNRS, Aix-Marseille University, Marseille, France.ORCID 0000-0003-3818-6907

Funding

Agence Nationale de la Recherche ANR-21-CE44-0024-MetCopAgence Nationale de la Recherche ANR-24-CE15-2449-ROSCop
6 · The paper itself

Abstract

The periplasmic multicopper oxidase CueO plays a crucial role in copper detoxification in enterobacteria. CueO contains a catalytic site, the Cu-T1 center, and a methionine-rich (Met-rich) domain capable of binding copper. This enzyme oxidizes cuprous ions (Cu

Indexed as

CopperEscherichia coliEscherichia coli ProteinsOxidoreductasesAnaerobiosisBacterial ProteinsHomeostasisOxidation-ReductionSalmonella typhimuriumBacterial ProteinsCopA protein, BacteriaCoppercueO protein, E coliEscherichia coli ProteinsOxidoreductasesanaerobic conditionscopper homeostasisenterobacteriamulticopper oxidase

Identifiers

PMID40624827
PMCPMC12510620

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.