Evidence map›Paper›PMID 40624712›Full record

ArticleEnvironmental health : a global access science source2025

Higher plasma AFB1 concentration is associated with increased risk of HPV 16 and HPV 18 detection and persistence among Ugandan women.

Yan Tong, Miriam Nakalembe, Collins Mpamani, Carolyn Nakisige, Jane Namugga, Grace Banturaki, Philiph Tonui, Omenge Orang'o, Kapten Muthoka, Anthony Ngeresa and 6 more

Abstract read
In one paragraph

Article in Environmental health : a global access science source, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Yan Tong *Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Miriam Nakalembe *Department of Obstetrics and Gynaecology, Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Collins MpamaniDepartment of Obstetrics and Gynaecology, Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Carolyn NakisigeDepartment of Obstetrics and Gynaecology, Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Jane NamuggaDepartment of Obstetrics and Gynaecology, Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Grace BanturakiDepartment of Obstetrics and Gynaecology, Infectious Diseases Institute, Makerere University, Kampala, Uganda.
Philiph TonuiDepartment of Reproductive Health, Moi University, Eldoret, Kenya.
Omenge Orang'oDepartment of Obstetrics and Gynecology, Medical College, Aga Khan University, Nairobi, Kenya.
Kapten MuthokaAcademic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.
Anthony NgeresaAcademic Model Providing Access to Healthcare (AMPATH), Eldoret, Kenya.
John GroopmanDepartment of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA.
Sean BurkeDepartment of Environmental Health and Engineering, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA.
Aaron ErmelDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Beverly MusickDepartment of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, IN, 46202, USA.
Patrick LoehrerDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.
Darron R BrownDepartment of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. darbrow@gmail.com.

Funding

Translational Biology CoreU54CA190151 · NCI · INDIANA UNIVERSITY INDIANAPOLIS · PI BROWN, DARRON R, LOEHRER, PATRICK J. · 2014 to 2019
$3.8M
NCI NIH HHS 1U54CA190151-01NCI NIH HHS U54 CA190151
6 · The paper itself

Abstract

introductionAflatoxins are environmental hazards; potent carcinogenic and immunosuppressive agents that contaminates corn and other crops. A high proportion of hepatocellular carcinoma cases are caused by exposure to dietary aflatoxins. Cervical cancer is common among Ugandan women; this malignancy is caused by persistent infection with oncogenic HPV types. An analysis was performed to examine associations between plasma aflatoxin B

methodsUgandan women were enrolled in a prospective cohort study. Annual cervical swabs (Enrollment, Month 12 and Month 24) were tested for oncogenic HPV. Plasma AFB

resultsThe analytical sample consisted of 114 women with a mean age of 33.2 years; 60 women were living with HIV; 59 were receiving antiretroviral therapy (ART) at enrollment. AFB

conclusionsAFB

Indexed as

Aflatoxin B1Human papillomavirus 16Human papillomavirus 18Papillomavirus InfectionsAdolescentAdultFemaleHumansMiddle AgedProspective StudiesUgandaUterine Cervical NeoplasmsYoung AdultAflatoxin B1

Identifiers

PMID40624712
PMCPMC12235798

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.