ArticleBMC ophthalmology2025
Analysis of the correlation between mental status and ocular and systemic indicators in patients with primary angle-closure glaucoma.
Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundTo analyze the poor mental status of patients with primary closed-angle glaucoma(PACG), and to explore the correlation between mental status and ocular and systemic indices in patients with PACG.
methodsWe collected patients' axial length (AL), anterior chamber depth (ACD), nerve fiber layer thickness (RNFL), cup-to-disc ratio (C/D), antinuclear antibody (ANA), toxoplasmosis antibody (anti-Toxoplasma gondii IgM), and anxiety and depression scores (HAMA and HAMD scales). Statistical analysis was utilized to analyze the data for each of the patients in the PACG and cataract patient groups.
resultsThe results showed that there was a statistically significant difference between the glaucoma group and the cataract group in terms of anxiety and depression scores, AL, ACD, RNFL, C/D, ANA, and Anti-Toxo IgM (P < 0.05). Anxiety scores of glaucoma patients were positively correlated with AL and C/D (P < 0.05), negatively correlated with RNFL (P < 0.05), and correlation existed with ANA and Anti-Toxo IgM (Eta
conclusionPatients with primary angle-closure glaucoma have higher anxiety and depression scores than the general population, and clinically we can predict the patient's mental status by their ocular and systemic indicators so that appropriate treatment can be taken in time.
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