ArticleBMC nephrology2025
Unveiling hidden contaminants: a systematic quantification and characterization of microplastics in hemodialysis and peritoneal dialysis fluids.
Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Micro- and Nanoplastics as Environmental Stressors: Mechanistic Links Among Gut Dysbiosis, Inflammation, and Systemic Health Effects.Journal of xenobiotics · 2026Review
- Micro- and Nanoplastic Pollution and Renal Health: Human Evidence, Mechanisms, and Clinical Implications.Journal of xenobiotics · 2026Review
- Article
- Effects of micro and nano plastics on renal health.World journal of nephrology · 2026Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microplastics (MPs) are an emerging environmental and biomedical concern due to their potential bioaccumulation and toxic effects. Given the extensive exposure of dialysis patients to large volumes of dialysate and water, the presence of MPs in dialysis solutions raises concerns regarding chronic exposure and systemic implications. This study systematically quantifies and characterizes MPs in hemodialysis (HD) and peritoneal dialysis (PD) fluids, investigating their sources and potential health risks. A total of 30 dialysis solution samples were analysed (revealing 36 suspect particles) using advanced spectroscopic techniques, including Fourier-transform infrared (FT-IR) spectroscopy, to identify polymer compositions. MPs predominantly fibers, were detected in all tested solutions, with polyethylene (PE), polyvinyl chloride (PVC), and ethylene-vinyl acetate (EVA) as the primary polymers. Statistical analyses confirmed significant variability in MP contamination across different dialysis fluids. Hemodialysis and peritoneal dialysis solutions show no statistically significant difference in MP concentration (HD: 0.29 ± 0.16 mp.L⁻¹, PD: 0.34 ± 0.02 mp.L⁻¹, p = 0.86). MP particles in HD solutions (1.31 ± 0.98 mm) are significantly larger than those in PD solutions (0.64 ± 0.43 mm) (p = 0.030). Despite similar MP concentrations, PD patients are estimated to be exposed to ~ 50% more MPs weekly than HD patients (9.57 ± 5.28 vs. 14.28 ± 0.84 mp. L⁻¹, p < 0.001). These findings highlight a potential, yet underrecognized, source of MP exposure in dialysis patients, necessitating further investigation into the implications of chronic MP absorption on renal function and systemic health. Regulatory policies should prioritize improved filtration techniques, alternative polymer-free materials, and stricter quality control measures to mitigate MP contamination in medical solutions. Future research should explore the long-term effects of MP exposure in dialysis-dependent individuals and refine analytical methodologies for contamination assessment.
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Registered trials
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