SynthesisBMC rheumatology2025
Effects of high-intensity interval training on patients with inflammatory arthritis: a systematic review.
Synthesis in BMC rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite reports of clinical benefits, concerns persist about the stress associated with high-intensity interval training (HIIT) in patients with inflammatory arthritis (IA). This review aimed to assess the effects of HIIT on disease activity, immune function, symptoms, cardiorespiratory fitness (CRF), and overall health-related quality of life (HRQoL) in patients with IA.
methodsThe PubMed, CINAHL, Cochrane Library, Web of Science, and Scopus databases were searched for eligible randomised controlled trials (RCTs). Data were extracted on the impacts of HIIT on IA conditions (i.e. rheumatoid arthritis (RA), psoriatic arthritis (PsA), and axial spondyloarthritis (axSpA)). Cochrane risk of bias tool 2.0 and PEDro scale were used in this review. This review was registered with PROSPERO (CRD42024577039).
resultsOf 117 initial records, nine studies met the inclusion criteria, comprising 586 IA patients (HIIT = 285; controls = 301). Most studies (n = 8) reported stable disease activity, but one showed a slight decrease. Of four studies reporting pain/fatigue, pain scores remained unchanged in most studies (n = 3), except in one where there was a significant reduction in pain in the HIIT group (p < 0.05), and two studies reported a decrease in fatigue (p < 0.05). All studies evaluating CRF reported improvements, with one also indicating enhanced HRQoL. Body composition measures showed either reductions or no change, while imaging assessments in two studies revealed no significant differences.
conclusionHIIT appears safe for patients with IA and does not exacerbate disease activity. HIIT resulted in improvement in CRF parameters, alongside positive changes in HRQoL. However, more high-quality RCTs are needed due to limited research in this area.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.